A screening method for gastric cancer by oral microbiome detection

• Published in: Oncology reports Vol. 39; no. 5; pp. 2217 - 2224
• Main Authors: Sun, Jing‑Hua, Li, Xiao‑Lin, Yin, Jie, Li, Yi‑Hong, Hou, Ben‑Xiang, Zhang, Zhongtao
• Format: Journal Article
• Language: English
• Published: Greece Spandidos Publications 01.05.2018; Spandidos Publications UK Ltd
• Subjects: Adult; Aged; Bacteria; Bacteria - classification; Bacteria - genetics; Bacterial infections; Biopsy; Campylobacter; Care and treatment; Dental Plaque - microbiology; Deoxyribonucleic acid; Diagnosis; Disease; DNA; Early Detection of Cancer - methods; Endoscopy; Ethics; Female; Gastric cancer; Gastroesophageal reflux; Health aspects; High-Throughput Nucleotide Sequencing; Hospitals; Host-bacteria relationships; Humans; Identification and classification; Male; Medical screening; Microbiota (Symbiotic organisms); Microorganisms; Middle Aged; Mortality; Pathogenesis; Patients; Phylogeny; Population; RNA, Ribosomal, 16S - genetics; Saliva - microbiology; Sample size; Sensitivity and Specificity; Sequence Analysis, DNA; Statistical analysis; Stomach cancer; Stomach Neoplasms - diagnosis; Stomach Neoplasms - microbiology; Teeth; Beijing China; China

Gastric cancer is the second most common malig-nancy and one of the principal causes of cancer‑related mortality worldwide. Early diagnostic and screening methods for gastric cancer are limited at present, most of them involving invasive procedures. We aimed to investigate the characteristics of the...