Biomaterial-Assisted Regenerative Medicine

This review aims to show case recent regenerative medicine based on biomaterial technologies. Regenerative medicine has arousing substantial interest throughout the world, with “The enhancement of cell activity” one of the essential concepts for the development of regenerative medicine. For example,...

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Published inInternational journal of molecular sciences Vol. 22; no. 16; p. 8657
Main Authors Nii, Teruki, Katayama, Yoshiki
Format Journal Article
LanguageEnglish
Published Basel MDPI AG 12.08.2021
MDPI
Subjects
Acids
Biomaterials
Biomedical materials
Breast cancer
Cartilage
Cell culture
cell transplantation
Cell viability
Collagen
drug research
Drug screening
Enzymes
Fibroblasts
Growth factors
Hydrogels
In vivo methods and tests
Medicine
Nonwoven fabrics
Permeability
Polymers
Regenerative medicine
Review
Skin
Spheroids
Tissue engineering
Transplantation
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Abstract This review aims to show case recent regenerative medicine based on biomaterial technologies. Regenerative medicine has arousing substantial interest throughout the world, with “The enhancement of cell activity” one of the essential concepts for the development of regenerative medicine. For example, drug research on drug screening is an important field of regenerative medicine, with the purpose of efficient evaluation of drug effects. It is crucial to enhance cell activity in the body for drug research because the difference in cell condition between in vitro and in vivo leads to a gap in drug evaluation. Biomaterial technology is essential for the further development of regenerative medicine because biomaterials effectively support cell culture or cell transplantation with high cell viability or activity. For example, biomaterial-based cell culture and drug screening could obtain information similar to preclinical or clinical studies. In the case of in vivo studies, biomaterials can assist cell activity, such as natural healing potential, leading to efficient tissue repair of damaged tissue. Therefore, regenerative medicine combined with biomaterials has been noted. For the research of biomaterial-based regenerative medicine, the research objective of regenerative medicine should link to the properties of the biomaterial used in the study. This review introduces regenerative medicine with biomaterial.
AbstractList This review aims to show case recent regenerative medicine based on biomaterial technologies. Regenerative medicine has arousing substantial interest throughout the world, with “The enhancement of cell activity” one of the essential concepts for the development of regenerative medicine. For example, drug research on drug screening is an important field of regenerative medicine, with the purpose of efficient evaluation of drug effects. It is crucial to enhance cell activity in the body for drug research because the difference in cell condition between in vitro and in vivo leads to a gap in drug evaluation. Biomaterial technology is essential for the further development of regenerative medicine because biomaterials effectively support cell culture or cell transplantation with high cell viability or activity. For example, biomaterial-based cell culture and drug screening could obtain information similar to preclinical or clinical studies. In the case of in vivo studies, biomaterials can assist cell activity, such as natural healing potential, leading to efficient tissue repair of damaged tissue. Therefore, regenerative medicine combined with biomaterials has been noted. For the research of biomaterial-based regenerative medicine, the research objective of regenerative medicine should link to the properties of the biomaterial used in the study. This review introduces regenerative medicine with biomaterial.
Author Nii, Teruki
Katayama, Yoshiki
AuthorAffiliation 5 Department of Biomedical Engineering, Chung Yuan Christian University, 200 Chung Pei Rd., Chung Li 32023, Taiwan
1 Department of Applied Chemistry, Faculty of Engineering, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan
3 Center for Future Chemistry, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan
2 Graduate School of Systems Life Sciences, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan
4 International Research Center for Molecular Systems, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan
AuthorAffiliation_xml – name: 2 Graduate School of Systems Life Sciences, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan
– name: 1 Department of Applied Chemistry, Faculty of Engineering, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan
– name: 4 International Research Center for Molecular Systems, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan
– name: 3 Center for Future Chemistry, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan
– name: 5 Department of Biomedical Engineering, Chung Yuan Christian University, 200 Chung Pei Rd., Chung Li 32023, Taiwan
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Snippet This review aims to show case recent regenerative medicine based on biomaterial technologies. Regenerative medicine has arousing substantial interest...
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SubjectTerms Acids
Biomaterials
Biomedical materials
Breast cancer
Cartilage
Cell culture
cell transplantation
Cell viability
Collagen
drug research
Drug screening
Enzymes
Fibroblasts
Growth factors
Hydrogels
In vivo methods and tests
Medicine
Nonwoven fabrics
Permeability
Polymers
Regenerative medicine
Review
Skin
Spheroids
Tissue engineering
Transplantation
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Title Biomaterial-Assisted Regenerative Medicine
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