CISD1 inhibits ferroptosis by protection against mitochondrial lipid peroxidation - Yuan, Hua; Li, Xuemei; Zhang, Xiuying; Kang, Rui; Tang, Daolin (Biochemical and biophysical research communications, 2016)
Keywords: Apoptosis - drug effects; Apoptosis - genetics; Apoptosis Regulatory Proteins - agonists; Apoptosis Regulatory Proteins - antagonists & inhibitors; Apoptosis Regulatory Proteins - genetics; Apoptosis Regulatory Proteins - metabolism; cell death; CISD1; Deferoxamine - pharmacology; Ferroptosis; Gene Expression Regulation, Neoplastic; Hep G2 Cells; hepatoma; Humans; iron; Iron - metabolism; Iron Chelating Agents - pharmacology; Iron-sulfur proteins; Lipid peroxidation; Lipid Peroxidation - drug effects; membrane proteins; Mitochondria; Mitochondria - drug effects; Mitochondria - metabolism; mitochondrial membrane; Mitochondrial Proteins - agonists; Mitochondrial Proteins - antagonists & inhibitors; Mitochondrial Proteins - genetics; Mitochondrial Proteins - metabolism; neoplasm cells; Oxidative Stress; Piperazines - antagonists & inhibitors; Piperazines - pharmacology; sulfur; Thiazolidinediones - pharmacology; Iron-sulfur proteins; GPX4; IRP; CISD1; Lipid peroxidation; Q-PCR; Ferroptosis; HCC; MDA; DFO; Mitochondria; Fe2; NRF2; ΔΨm; ROS; VDACs; CCK-8; GSH