Androgen receptor (CAG)n repeat polymorphism contributes to risk of sudden cardiac death originated from coronary artery disease with sex discrepancy

• Published in: Forensic science international Vol. 343; p. 111563
• Main Authors: Zhen, Xiaoyuan, Zhao, Wenfeng, Wang, Jiawen, Li, Lijuan, He, Yan, Zhang, Jianhua, Li, Chengtao, Zhang, Suhua, Luo, Bin, Huang, Jiang, Gao, Yuzhen
• Format: Journal Article
• Language: English
• Published: Ireland Elsevier B.V 01.02.2023; Elsevier Limited
• Subjects: (CAG)n repeat polymorphism; Alleles; Androgen receptor; Androgen receptors; Androgens; Autopsies; Cardiovascular disease; Cardiovascular diseases; Confidence intervals; Coronary artery disease; Coronary Artery Disease - complications; Coronary Artery Disease - genetics; Coronary vessels; Death; Death, Sudden, Cardiac - epidemiology; Death, Sudden, Cardiac - etiology; Disease prevention; Epidemiology; Etiology; Female; Females; Forensic sciences; Gender differences; Gene polymorphism; Genes; Genetic markers; Genetic Predisposition to Disease; Genetic susceptibility; Genetic testing; Health care; Heart diseases; Humans; Male; Males; Mortality; Phenotypes; Phenotypic variations; Polyglutamine; Polymorphism; Polymorphism, Genetic; Populations; Public health; Receptors; Receptors, Androgen - genetics; Risk; Sex; Sex discrepancy; Software; Sudden cardiac death; Trinucleotide repeats; Vein & artery diseases; China; (CAG)n repeat polymorphism; Sex discrepancy; Genetic susceptibility; Sudden cardiac death; Coronary artery disease; Androgen receptor; (CAG)(n) repeat polymorphism

Sudden cardiac death (SCD) is the leading cause of natural death worldwide which is responsible for almost half of all heart disease deaths, making it a substantial public health problem. Previous epidemiological studies from different countries have demonstrated the significant SCD incident differe...