Accuracy of Anti-SARS-CoV-2 Antibody in Comparison with Surrogate Viral Neutralization Test in Persons Living with HIV, Systemic Lupus Erythematosus, and Chronic Kidney Disease

• Published in: Vaccines (Basel) Vol. 12; no. 5; p. 558
• Main Authors: Tiara, Marita Restie, Prayuda, Chrisan Bimo, Maulidya, Tara Titian, Djauhari, Hofiya, Suhendar, Dadang, Wisaksana, Rudi, Hamijoyo, Laniyati, Supriyadi, Rudi, Indrati, Agnes Rengga, Alisjahbana, Bachti
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 01.05.2024
• Subjects: Accuracy; Analysis; Antibodies; antibody; Antigens; Autoimmune diseases; Chronic conditions; Chronic kidney failure; Comorbidity; Coronaviruses; Correlation analysis; COVID-19; COVID-19 vaccines; Development and progression; Disease transmission; Health aspects; HIV; HIV (Viruses); HIV infection; Human immunodeficiency virus; Immunoassay; Infections; Kidney diseases; Kidneys; Lupus; Methods; mRNA vaccines; Neutralization; Pandemics; Serology; Severe acute respiratory syndrome; Severe acute respiratory syndrome coronavirus 2; Systemic lupus erythematosus; Testing; Vaccination; Viral antibodies; Viral diseases; China; Taiwan; Indonesia; COVID-19; antibody; immunoassay; vaccination

The presence of the anti-SARS-CoV-2-RBD antibody (anti-RBD) prevents severe COVID-19. We aimed to determine the accuracy of a point-of-care anti-RBD testing implemented in persons living with HIV (PLWH), systemic lupus erythematosus (SLE), and chronic kidney disease (CKD). We enrolled 182 non-comorb...