Population model analysis of chiral inversion and degradation of bupropion enantiomers, and application to enantiomer specific fraction unbound determination in rat plasma and brain - Bhattacharya, Chandrali; Masters, Andrea R.; Bach, Christine; Stratford, Robert E. (Journal of pharmaceutical and biomedical analysis, 2021)
Keywords: Animals; Bioanalysis; Brain; Bupropion; Chiral inversion; In vitro model; Kinetics; Pharmaceutical Preparations; Pharmacokinetic modeling; Protein binding; Rats; Stereoisomerism; Bupropion; Bioanalysis; In vitro model; Kinetics; Chiral inversion; Pharmacokinetic modeling; Protein binding