Mitochondrial Dysfunction Plays Central Role in Nonalcoholic Fatty Liver Disease

• Published in: International journal of molecular sciences Vol. 23; no. 13; p. 7280
• Main Authors: Ramanathan, Raghu, Ali, Ahmad Hassan, Ibdah, Jamal A.
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 30.06.2022; MDPI
• Subjects: Alcohol use; Body fat; Diabetes; Diet; Drug development; Fatty acids; Fatty liver; Insulin resistance; Lipids; Liver cancer; Liver cirrhosis; Liver diseases; Microbiota; Obesity; Oxidative stress; Pathogenesis; Proteins; Review; Risk factors; Triglycerides; United States > US

Nonalcoholic fatty liver disease (NAFLD) is a global pandemic that affects one-quarter of the world’s population. NAFLD includes a spectrum of progressive liver disease from steatosis to nonalcoholic steatohepatitis (NASH), fibrosis, and cirrhosis and can be complicated by hepatocellular carcinoma....