Emerging roles of neutrophil-borne S100A8/A9 in cardiovascular inflammation

• Published in: Pharmacological research Vol. 161; p. 105212
• Main Authors: Sreejit, Gopalkrishna, Abdel Latif, Ahmed, Murphy, Andrew J., Nagareddy, Prabhakara R.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ltd 01.11.2020
• Subjects: Cardiac Inflammation; DAMPs; Myocardial Infarction; Neutrophils; S100A8/A9; S100A8/A9; Myocardial Infarction; Cardiac Inflammation; Neutrophils; DAMPs

Elevated neutrophil count is associated with higher risk of major adverse cardiac events including myocardial infarction and early development of heart failure. Neutrophils contribute to cardiac damage through a number of mechanisms, including attraction of other immune cells and release of inflamma...