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Abstract In December 2019, an outbreak of coronavirus disease 2019 (COVID-19) due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) began in China and spread rapidly worldwide. It is unknown whether hemodialysis patients represent a distinct group of patients with certain characteristics that may make them susceptible to infection or severe disease. In this case report, we describe the clinical and epidemiologic features of COVID-19 infection in 201 maintenance hemodialysis patients in Zhongnan Hospital of Wuhan University, including 5 maintenance hemodialysis patients who contracted COVID-19 infection. Of the 5 patients with COVID-19 infection, one had a definite history of contact with an infected person. The age range of the patients was 47 to 67 years. Diarrhea (80%), fever (60%), and fatigue (60%) were the most common symptoms. Lymphopenia occurred in all patients. Computed tomography of the chest showed ground glass opacity in the lungs of all patients. Up to February 13, 2020, none of the patients had developed severe complications (acute respiratory distress syndrome, shock, or multiple organ dysfunction) or died.
AbstractList In December 2019, an outbreak of coronavirus disease 2019 (COVID-19) due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) began in China and spread rapidly worldwide. It is unknown whether hemodialysis patients represent a distinct group of patients with certain characteristics that may make them susceptible to infection or severe disease. In this case report, we describe the clinical and epidemiologic features of COVID-19 infection in 201 maintenance hemodialysis patients in Zhongnan Hospital of Wuhan University, including 5 maintenance hemodialysis patients who contracted COVID-19 infection. Of the 5 patients with COVID-19 infection, one had a definite history of contact with an infected person. The age range of the patients was 47 to 67 years. Diarrhea (80%), fever (60%), and fatigue (60%) were the most common symptoms. Lymphopenia occurred in all patients. Computed tomography of the chest showed ground glass opacity in the lungs of all patients. Up to February 13, 2020, none of the patients had developed severe complications (acute respiratory distress syndrome, shock, or multiple organ dysfunction) or died.
In December 2019, an outbreak of coronavirus disease 2019 (COVID-19) due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) began in China and spread rapidly worldwide. It is unknown whether hemodialysis patients represent a distinct group of patients with certain characteristics that may make them susceptible to infection or severe disease. In this case report, we describe the clinical and epidemiologic features of COVID-19 infection in 201 maintenance hemodialysis patients in Zhongnan Hospital of Wuhan University, including 5 maintenance hemodialysis patients who contracted COVID-19 infection. Of the 5 patients with COVID-19 infection, one had a definite history of contact with an infected person. The age range of the patients was 47 to 67 years. Diarrhea (80%), fever (60%), and fatigue (60%) were the most common symptoms. Lymphopenia occurred in all patients. Computed tomography of the chest showed ground glass opacity in the lungs of all patients. Up to February 13, 2020, none of the patients had developed severe complications (acute respiratory distress syndrome, shock, or multiple organ dysfunction) or died.In December 2019, an outbreak of coronavirus disease 2019 (COVID-19) due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) began in China and spread rapidly worldwide. It is unknown whether hemodialysis patients represent a distinct group of patients with certain characteristics that may make them susceptible to infection or severe disease. In this case report, we describe the clinical and epidemiologic features of COVID-19 infection in 201 maintenance hemodialysis patients in Zhongnan Hospital of Wuhan University, including 5 maintenance hemodialysis patients who contracted COVID-19 infection. Of the 5 patients with COVID-19 infection, one had a definite history of contact with an infected person. The age range of the patients was 47 to 67 years. Diarrhea (80%), fever (60%), and fatigue (60%) were the most common symptoms. Lymphopenia occurred in all patients. Computed tomography of the chest showed ground glass opacity in the lungs of all patients. Up to February 13, 2020, none of the patients had developed severe complications (acute respiratory distress syndrome, shock, or multiple organ dysfunction) or died.
Author Wei, Zimeng
He, Hong
Liao, Cong
Hu, Chun
Zhang, Chengjie
Shui, Hua
Hong, Zixi
Wang, Rui
Liao, Meiyan
Author_xml – sequence: 1
  givenname: Rui
  surname: Wang
  fullname: Wang, Rui
  organization: Department of Nephrology, Zhongnan Hospital, Wuhan University, Wuhan, China
– sequence: 2
  givenname: Cong
  surname: Liao
  fullname: Liao, Cong
  organization: Laboratory Medicine, Zhongnan Hospital, Wuhan University, Wuhan, China
– sequence: 3
  givenname: Hong
  surname: He
  fullname: He, Hong
  organization: Department of Nephrology, Zhongnan Hospital, Wuhan University, Wuhan, China
– sequence: 4
  givenname: Chun
  surname: Hu
  fullname: Hu, Chun
  organization: Department of Nephrology, Zhongnan Hospital, Wuhan University, Wuhan, China
– sequence: 5
  givenname: Zimeng
  surname: Wei
  fullname: Wei, Zimeng
  organization: Department of Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, China
– sequence: 6
  givenname: Zixi
  surname: Hong
  fullname: Hong, Zixi
  organization: Department of Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, China
– sequence: 7
  givenname: Chengjie
  surname: Zhang
  fullname: Zhang, Chengjie
  organization: Department of Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, China
– sequence: 8
  givenname: Meiyan
  surname: Liao
  fullname: Liao, Meiyan
  organization: Imaging Department, Zhongnan Hospital, Wuhan University, Wuhan, China
– sequence: 9
  givenname: Hua
  surname: Shui
  fullname: Shui, Hua
  email: shuihua@whu.edu.cn
  organization: Department of Nephrology, Zhongnan Hospital, Wuhan University, Wuhan, China
BackLink https://www.ncbi.nlm.nih.gov/pubmed/32240718$$D View this record in MEDLINE/PubMed
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ContentType Journal Article
Copyright 2020 National Kidney Foundation, Inc.
Copyright © 2020 National Kidney Foundation, Inc. Published by Elsevier Inc. All rights reserved.
2020 by the National Kidney Foundation, Inc. 2020 National Kidney Foundation, Inc.
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Keywords COVID-19
symptoms
SARS-CoV-2
Hemodialysis
end-stage renal disease (ESRD)
coronavirus
case report
chest radiograph
diarrhea
Language English
License Copyright © 2020 National Kidney Foundation, Inc. Published by Elsevier Inc. All rights reserved.
Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
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Snippet In December 2019, an outbreak of coronavirus disease 2019 (COVID-19) due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) began in China and...
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SubjectTerms Aged
Betacoronavirus
Case Report
chest radiograph
China - epidemiology
coronavirus
Coronavirus Infections - complications
Coronavirus Infections - diagnosis
Coronavirus Infections - epidemiology
COVID-19
diarrhea
Disease Outbreaks
end-stage renal disease (ESRD)
Female
Hemodialysis
Humans
Kidney Failure, Chronic - etiology
Kidney Failure, Chronic - therapy
Lung - diagnostic imaging
Male
Middle Aged
Pandemics
Pneumonia, Viral - complications
Pneumonia, Viral - diagnosis
Pneumonia, Viral - epidemiology
Renal Dialysis - methods
SARS-CoV-2
symptoms
Tomography, X-Ray Computed
Treatment Outcome
Title COVID-19 in Hemodialysis Patients: A Report of 5 Cases
URI https://dx.doi.org/10.1053/j.ajkd.2020.03.009
https://www.ncbi.nlm.nih.gov/pubmed/32240718
https://www.proquest.com/docview/2386281474/abstract/
https://pubmed.ncbi.nlm.nih.gov/PMC7118604
Volume 76
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