Vaccine delivery systems toward lymph nodes

• Published in: Advanced drug delivery reviews Vol. 179; p. 113914
• Main Authors: Ding, Yingyue, Li, Zhaoting, Jaklenec, Ana, Hu, Quanyin
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.12.2021
• Subjects: Adaptive Immunity - immunology; Antigens - metabolism; Delivery barriers; Drug Administration Routes; Drug Delivery Systems - methods; Humans; Immune response; Lymph nodes; Lymph Nodes - immunology; Lymph Nodes - physiology; Lymphocytes; Nanoparticle Drug Delivery System - chemistry; Targeted delivery; Vaccine; Vaccines - administration & dosage; Vaccines - immunology; Vaccine; Delivery barriers; Immune response; Targeted delivery; Lymphocytes; Lymph nodes

Vaccines play an important role in the control and prevention of human infectious diseases such as the ongoing COVID-19 pandemic. The successful vaccination needs to effectively deliver antigenic substances to induce a strong protective or therapeutic immune response. In this review, the lymph node...