Virome Diversity Correlates with Intestinal Microbiome Diversity in Adult Monozygotic Twins

• Published in: Cell host & microbe Vol. 25; no. 2; pp. 261 - 272.e5
• Main Authors: Moreno-Gallego, J. Leonardo, Chou, Shao-Pei, Di Rienzi, Sara C., Goodrich, Julia K., Spector, Timothy D., Bell, Jordana T., Youngblut, Nicholas D., Hewson, Ian, Reyes, Alejandro, Ley, Ruth E.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 13.02.2019
• Subjects: Adult; Base Sequence; concordant and discordant monozygotic twins; DNA, Bacterial - genetics; DNA, Viral - genetics; Feces - microbiology; Feces - virology; Gastrointestinal Microbiome - genetics; Gastrointestinal Microbiome - physiology; Genetic Variation - genetics; human gut microbiome; human gut virome; Humans; Phylogeny; RNA, Ribosomal, 16S - genetics; Sequence Alignment; Twins, Monozygotic; human gut virome; concordant and discordant monozygotic twins; human gut microbiome

The virome is one of the most variable components of the human gut microbiome. Within twin pairs, viromes have been shown to be similar for infants, but not for adults, indicating that as twins age and their environments and microbiomes diverge, so do their viromes. The degree to which the microbiom...