An oncogenic axis of STAT-mediated BATF3 upregulation causing MYC activity in classical Hodgkin lymphoma and anaplastic large cell lymphoma

Classical Hodgkin lymphoma (cHL) and anaplastic large cell lymphoma (ALCL) feature high expression of activator protein-1 (AP-1) transcription factors, which regulate various physiological processes but also promote lymphomagenesis. The AP-1 factor basic leucine zipper transcription factor, ATF-like...

Full description

Saved in:
Bibliographic Details
Published inLeukemia Vol. 32; no. 1; pp. 92 - 101
Main Authors Lollies, A, Hartmann, S, Schneider, M, Bracht, T, Weiß, A L, Arnolds, J, Klein-Hitpass, L, Sitek, B, Hansmann, M-L, Küppers, R, Weniger, M A
Format Journal Article
LanguageEnglish
Published London Nature Publishing Group UK 01.01.2018
Nature Publishing Group
Subjects
13
13/31
13/44
13/51
13/89
13/95
631/45/612/822
631/67/1990/291/1556
631/67/1990/291/1621
631/67/395
631/80/86
82
Activator protein 1
Anaplastic large-cell lymphoma
B-cell lymphoma
Basic-Leucine Zipper Transcription Factors - genetics
Cancer Research
Carcinogenesis - genetics
Carcinogenesis - pathology
Care and treatment
CD30 antigen
Cell Line, Tumor
Cell Proliferation - genetics
Cell Survival
Chromatin
Critical Care Medicine
Development and progression
Gene expression
Gene Expression Regulation, Neoplastic - genetics
Genetic aspects
Health aspects
Hematology
Hodgkin Disease - genetics
Hodgkin Disease - pathology
Hodgkin's lymphoma
Humans
Immunoprecipitation
Intensive
Interleukin 13
Internal Medicine
Janus kinase 2
Janus Kinase 2 - genetics
JunB protein
Leucine
Leucine zipper proteins
Lymphocytes B
Lymphoma
Lymphoma, Large B-Cell, Diffuse - genetics
Lymphoma, Large B-Cell, Diffuse - pathology
Lymphoma, Large-Cell, Anaplastic - genetics
Lymphoma, Large-Cell, Anaplastic - pathology
Lymphomas
Mass spectrometry
Mass spectroscopy
Medicine
Medicine & Public Health
Myc protein
Oncogenes - genetics
Oncology
original-article
Physiological effects
Promoter Regions, Genetic - genetics
Proteins
Proto-Oncogene Proteins c-myc - genetics
RNA, Small Interfering - genetics
Signal Transduction - genetics
Signaling
STAT Transcription Factors - genetics
Survival
Transcription Factor AP-1 - genetics
Transcription factors
Transcriptional Activation - genetics
Up-Regulation - genetics
Online AccessGet full text

Cover

Abstract Classical Hodgkin lymphoma (cHL) and anaplastic large cell lymphoma (ALCL) feature high expression of activator protein-1 (AP-1) transcription factors, which regulate various physiological processes but also promote lymphomagenesis. The AP-1 factor basic leucine zipper transcription factor, ATF-like 3 (BATF3), is highly transcribed in cHL and ALCL; however, its functional importance in lymphomagenesis is unknown. Here we show that proto-typical CD30 + lymphomas, namely cHL (21/30) and primary mediastinal B-cell lymphoma (8/9), but also CD30 + diffuse large B-cell lymphoma (15/20) frequently express BATF3 protein. Mass spectrometry and co-immunoprecipitation established interactions of BATF3 with JUN and JUNB in cHL and ALCL lines. BATF3 knockdown using short hairpin RNAs was toxic for cHL and ALCL lines, reducing their proliferation and survival. We identified MYC as a critical BATF3 target and confirmed binding of BATF3 to the MYC promoter. JAK/STAT signaling regulated BATF3 expression, as chemical JAK2 inhibition reduced and interleukin 13 stimulation induced BATF3 expression in cHL lines. Chromatin immunoprecipitation substantiated a direct regulation of BATF3 by STAT proteins in cHL and ALCL lines. In conclusion, we identified STAT-mediated BATF3 expression that is essential for lymphoma cell survival and promoted MYC activity in cHL and ALCL, hence we recognized a new oncogenic axis in these lymphomas.
AbstractList Classical Hodgkin lymphoma (cHL) and anaplastic large cell lymphoma (ALCL) feature high expression of activator protein-1 (AP-1) transcription factors, which regulate various physiological processes but also promote lymphomagenesis. The AP-1 factor basic leucine zipper transcription factor, ATF-like 3 (BATF3), is highly transcribed in cHL and ALCL; however, its functional importance in lymphomagenesis is unknown. Here we show that proto-typical CD30+ lymphomas, namely cHL (21/30) and primary mediastinal B-cell lymphoma (8/9), but also CD30+ diffuse large B-cell lymphoma (15/20) frequently express BATF3 protein. Mass spectrometry and co-immunoprecipitation established interactions of BATF3 with JUN and JUNB in cHL and ALCL lines. BATF3 knockdown using short hairpin RNAs was toxic for cHL and ALCL lines, reducing their proliferation and survival. We identified MYC as a critical BATF3 target and confirmed binding of BATF3 to the MYC promoter. JAK/STAT signaling regulated BATF3 expression, as chemical JAK2 inhibition reduced and interleukin 13 stimulation induced BATF3 expression in cHL lines. Chromatin immunoprecipitation substantiated a direct regulation of BATF3 by STAT proteins in cHL and ALCL lines. In conclusion, we identified STAT-mediated BATF3 expression that is essential for lymphoma cell survival and promoted MYC activity in cHL and ALCL, hence we recognized a new oncogenic axis in these lymphomas.
Classical Hodgkin lymphoma (cHL) and anaplastic large cell lymphoma (ALCL) feature high expression of activator protein-1 (AP-1) transcription factors, which regulate various physiological processes but also promote lymphomagenesis. The AP-1 factor basic leucine zipper transcription factor, ATF-like 3 (BATF3), is highly transcribed in cHL and ALCL; however, its functional importance in lymphomagenesis is unknown. Here we show that proto-typical CD30[sup.+] lymphomas, namely cHL (21/30) and primary mediastinal B-cell lymphoma (8/9), but also CD30[sup.+] diffuse large B-cell lymphoma (15/20) frequently express BATF3 protein. Mass spectrometry and co-immunoprecipitation established interactions of BATF3 with JUN and JUNB in cHL and ALCL lines. BATF3 knockdown using short hairpin RNAs was toxic for cHL and ALCL lines, reducing their proliferation and survival. We identified MYC as a critical BATF3 target and confirmed binding of BATF3 to the MYC promoter. JAK/STAT signaling regulated BATF3 expression, as chemical JAK2 inhibition reduced and interleukin 13 stimulation induced BATF3 expression in cHL lines. Chromatin immunoprecipitation substantiated a direct regulation of BATF3 by STAT proteins in cHL and ALCL lines. In conclusion, we identified STAT-mediated BATF3 expression that is essential for lymphoma cell survival and promoted MYC activity in cHL and ALCL, hence we recognized a new oncogenic axis in these lymphomas.
Classical Hodgkin lymphoma (cHL) and anaplastic large cell lymphoma (ALCL) feature high expression of activator protein-1 (AP-1) transcription factors, which regulate various physiological processes but also promote lymphomagenesis. The AP-1 factor basic leucine zipper transcription factor, ATF-like 3 (BATF3), is highly transcribed in cHL and ALCL; however, its functional importance in lymphomagenesis is unknown. Here we show that proto-typical CD30 + lymphomas, namely cHL (21/30) and primary mediastinal B-cell lymphoma (8/9), but also CD30 + diffuse large B-cell lymphoma (15/20) frequently express BATF3 protein. Mass spectrometry and co-immunoprecipitation established interactions of BATF3 with JUN and JUNB in cHL and ALCL lines. BATF3 knockdown using short hairpin RNAs was toxic for cHL and ALCL lines, reducing their proliferation and survival. We identified MYC as a critical BATF3 target and confirmed binding of BATF3 to the MYC promoter. JAK/STAT signaling regulated BATF3 expression, as chemical JAK2 inhibition reduced and interleukin 13 stimulation induced BATF3 expression in cHL lines. Chromatin immunoprecipitation substantiated a direct regulation of BATF3 by STAT proteins in cHL and ALCL lines. In conclusion, we identified STAT-mediated BATF3 expression that is essential for lymphoma cell survival and promoted MYC activity in cHL and ALCL, hence we recognized a new oncogenic axis in these lymphomas.
Classical Hodgkin lymphoma (cHL) and anaplastic large cell lymphoma (ALCL) feature high expression of activator protein-1 (AP-1) transcription factors, which regulate various physiological processes but also promote lymphomagenesis. The AP-1 factor basic leucine zipper transcription factor, ATF-like 3 (BATF3), is highly transcribed in cHL and ALCL; however, its functional importance in lymphomagenesis is unknown. Here we show that proto-typical CD30[sup.+] lymphomas, namely cHL (21/30) and primary mediastinal B-cell lymphoma (8/9), but also CD30[sup.+] diffuse large B-cell lymphoma (15/20) frequently express BATF3 protein. Mass spectrometry and co-immunoprecipitation established interactions of BATF3 with JUN and JUNB in cHL and ALCL lines. BATF3 knockdown using short hairpin RNAs was toxic for cHL and ALCL lines, reducing their proliferation and survival. We identified MYC as a critical BATF3 target and confirmed binding of BATF3 to the MYC promoter. JAK/STAT signaling regulated BATF3 expression, as chemical JAK2 inhibition reduced and interleukin 13 stimulation induced BATF3 expression in cHL lines. Chromatin immunoprecipitation substantiated a direct regulation of BATF3 by STAT proteins in cHL and ALCL lines. In conclusion, we identified STAT-mediated BATF3 expression that is essential for lymphoma cell survival and promoted MYC activity in cHL and ALCL, hence we recognized a new oncogenic axis in these lymphomas. Leukemia (2018) 32, 92-101; doi: 10.1038/leu.2017.203; published online 25 July 2017
Classical Hodgkin lymphoma (cHL) and anaplastic large cell lymphoma (ALCL) feature high expression of activator protein-1 (AP-1) transcription factors, which regulate various physiological processes but also promote lymphomagenesis. The AP-1 factor basic leucine zipper transcription factor, ATF-like 3 (BATF3), is highly transcribed in cHL and ALCL; however, its functional importance in lymphomagenesis is unknown. Here we show that proto-typical CD30 lymphomas, namely cHL (21/30) and primary mediastinal B-cell lymphoma (8/9), but also CD30 diffuse large B-cell lymphoma (15/20) frequently express BATF3 protein. Mass spectrometry and co-immunoprecipitation established interactions of BATF3 with JUN and JUNB in cHL and ALCL lines. BATF3 knockdown using short hairpin RNAs was toxic for cHL and ALCL lines, reducing their proliferation and survival. We identified MYC as a critical BATF3 target and confirmed binding of BATF3 to the MYC promoter. JAK/STAT signaling regulated BATF3 expression, as chemical JAK2 inhibition reduced and interleukin 13 stimulation induced BATF3 expression in cHL lines. Chromatin immunoprecipitation substantiated a direct regulation of BATF3 by STAT proteins in cHL and ALCL lines. In conclusion, we identified STAT-mediated BATF3 expression that is essential for lymphoma cell survival and promoted MYC activity in cHL and ALCL, hence we recognized a new oncogenic axis in these lymphomas.
Audience Academic
Author Lollies, A
Weniger, M A
Hartmann, S
Schneider, M
Klein-Hitpass, L
Bracht, T
Arnolds, J
Sitek, B
Hansmann, M-L
Küppers, R
Weiß, A L
Author_xml – sequence: 1
  givenname: A
  surname: Lollies
  fullname: Lollies, A
  organization: Institute of Cell Biology (Cancer Research), Faculty of Medicine, University of Duisburg-Essen
– sequence: 2
  givenname: S
  surname: Hartmann
  fullname: Hartmann, S
  organization: Dr Senckenberg Institute of Pathology, Goethe-University of Frankfurt, Medical School
– sequence: 3
  givenname: M
  surname: Schneider
  fullname: Schneider, M
  organization: Institute of Cell Biology (Cancer Research), Faculty of Medicine, University of Duisburg-Essen, Dr Senckenberg Institute of Pathology, Goethe-University of Frankfurt, Medical School
– sequence: 4
  givenname: T
  orcidid: 0000-0002-1194-6614
  surname: Bracht
  fullname: Bracht, T
  organization: Medizinisches Proteom-Center, Ruhr-University Bochum
– sequence: 5
  givenname: A L
  surname: Weiß
  fullname: Weiß, A L
  organization: Institute of Cell Biology (Cancer Research), Faculty of Medicine, University of Duisburg-Essen
– sequence: 6
  givenname: J
  surname: Arnolds
  fullname: Arnolds, J
  organization: Department of Otorhinolaryngology, Faculty of Medicine, University of Duisburg-Essen
– sequence: 7
  givenname: L
  surname: Klein-Hitpass
  fullname: Klein-Hitpass, L
  organization: Institute of Cell Biology (Cancer Research), Faculty of Medicine, University of Duisburg-Essen
– sequence: 8
  givenname: B
  surname: Sitek
  fullname: Sitek, B
  organization: Medizinisches Proteom-Center, Ruhr-University Bochum
– sequence: 9
  givenname: M-L
  surname: Hansmann
  fullname: Hansmann, M-L
  organization: Dr Senckenberg Institute of Pathology, Goethe-University of Frankfurt, Medical School
– sequence: 10
  givenname: R
  surname: Küppers
  fullname: Küppers, R
  email: ralf.kueppers@uk-essen.de
  organization: Institute of Cell Biology (Cancer Research), Faculty of Medicine, University of Duisburg-Essen
– sequence: 11
  givenname: M A
  surname: Weniger
  fullname: Weniger, M A
  email: marc.weniger@uk-essen.de
  organization: Institute of Cell Biology (Cancer Research), Faculty of Medicine, University of Duisburg-Essen
BackLink https://www.ncbi.nlm.nih.gov/pubmed/28659618$$D View this record in MEDLINE/PubMed
BookMark eNptksFu1DAQhi1URLeFG2dkCQlxIEvs2I5zDCtKkYo4sBw4RV7Hybo4drATxD4DL81EW0qLKsu2NPPN7xnPnKETH7xB6DnJ1yQv5Ftn5jXNSQlH8QitCCtFxjknJ2iVS1lmoqLsFJ2ldJ3ni1M8QadUCl4JIlfod-1x8Dr0xluN1S-bcOjwl229zQbTWjWZFr-rtxcFnsdo-tmpyQaPtZqT9T3-9G2DlZ7sTzsdsAW7UylZrRy-DG3_HSzuMIz7MCisfAtbjUBM8JRTsTdYG-dukafocadcMs9u7nP09eL9dnOZXX3-8HFTX2WacT5lbEeqjnc0Z2VLi4KVXIu2agmTpKJCS1O0nZCVqpg0Had8Vwq5U7rtWKllUZriHL0-6o4x_JhNmprBpiUT5U2YU0Mq0GKCEgroy__Q6zBHD9kBJeEHRV6Sf1SvnGms78IUlV5Em5pTSkopOQNq_QAFqzWD1dDUzoL9XsCrOwF7o9y0T8HNSwfSffDNEdQxpBRN14zRDioeGpI3y5A0MCTNMiRwFIC_uClq3kGTb-G_UwFAdgQSuHxv4p2qHxL8A-83xgw
CitedBy_id crossref_primary_10_1155_2020_8830123
crossref_primary_10_1186_s13045_023_01492_8
crossref_primary_10_18632_oncotarget_24639
crossref_primary_10_3390_cancers10040093
crossref_primary_10_1016_j_bbcan_2022_188802
crossref_primary_10_3390_ijms20071687
crossref_primary_10_3390_pathogens7030059
crossref_primary_10_1007_s00251_024_01335_x
crossref_primary_10_1038_s41588_023_01554_0
crossref_primary_10_3389_fimmu_2023_1270365
crossref_primary_10_3390_cancers14071650
crossref_primary_10_3390_cancers14112647
crossref_primary_10_1038_s41572_020_0189_6
crossref_primary_10_1038_s41586_022_05692_z
crossref_primary_10_3390_cancers10040107
crossref_primary_10_1002_jcb_28646
crossref_primary_10_3389_fimmu_2023_1155468
crossref_primary_10_18632_aging_202675
crossref_primary_10_3390_cancers13205147
crossref_primary_10_1007_s11033_023_09059_z
crossref_primary_10_1016_j_beha_2023_101514
crossref_primary_10_1111_bjh_15658
crossref_primary_10_1182_blood_2017_09_772632
crossref_primary_10_1080_10428194_2021_2015587
crossref_primary_10_1007_s12308_017_0303_1
crossref_primary_10_1186_s40164_020_00197_9
crossref_primary_10_4049_jimmunol_2000228
crossref_primary_10_3390_cancers10010021
crossref_primary_10_1016_j_trecan_2023_04_009
crossref_primary_10_1146_annurev_immunol_080223_044610
crossref_primary_10_1038_s41467_021_25379_9
crossref_primary_10_1007_s13273_023_00403_9
crossref_primary_10_3390_diagnostics11061123
crossref_primary_10_1038_s41385_020_0297_3
crossref_primary_10_1038_s41598_020_66224_1
crossref_primary_10_1172_JCI95993
crossref_primary_10_1186_s13046_018_0757_8
crossref_primary_10_1038_leu_2017_275
crossref_primary_10_1038_s41598_018_34199_9
crossref_primary_10_1038_s41375_021_01204_6
Cites_doi 10.1038/nm1249
10.1038/leu.2009.161
10.1146/annurev.pathol.4.110807.092209
10.1182/blood-2012-05-428896
10.1182/blood-2012-08-447375
10.1073/pnas.1406985111
10.1016/S0002-9440(10)63690-5
10.1182/blood-2012-06-439570
10.3324/haematol.11073
10.1038/nri3470
10.1182/blood-2002-08-2673
10.1038/nature11531
10.1084/jem.20080809
10.1007/BF03402041
10.1182/blood-2007-08-105643
10.1371/journal.pone.0026837
10.1073/pnas.1610970113
10.1158/1078-0432.CCR-11-1942
10.1074/jbc.M308617200
10.1038/sj.onc.1209151
10.1097/PAS.0000000000000365
10.1038/cddis.2012.49
10.1038/nature09671
10.1038/nature11530
10.1084/jem.184.4.1495
10.1200/JCO.2008.20.9759
10.1182/blood-2014-10-567461
10.1038/nm.2966
10.1182/blood-2014-08-594507
10.1016/j.ccr.2012.05.024
10.1182/blood-2008-01-134783
10.1038/modpathol.3800419
10.1182/blood-2007-09-111948
10.1038/ni.2455
10.1038/sj.onc.1205152
10.1093/emboj/cdf389
10.1158/1078-0432.CCR-07-4709
10.1038/nrc1209
10.1038/nature07064
10.1016/j.ccell.2015.03.006
10.3324/haematol.12875
10.1111/j.1365-2141.2007.06924.x
10.1182/blood.V99.2.618
10.1073/pnas.91.23.10962
10.1158/0008-5472.CAN-05-0925
10.1111/bjh.13079
10.1084/jem.20031074
10.1126/science.1164206
10.1038/ng.2900
10.1038/ni.2428
10.1097/01.pas.0000213412.25935.e4
10.1038/mt.2008.6
10.1002/gcc.22331
10.1182/blood-2007-04-087734
10.1046/j.1365-2141.2002.03456.x
10.1016/j.ccr.2010.11.013
10.1182/blood.V66.4.848.848
ContentType Journal Article
Copyright Macmillan Publishers Limited, part of Springer Nature. 2018
COPYRIGHT 2018 Nature Publishing Group
Copyright Nature Publishing Group Jan 2018
Copyright_xml – notice: Macmillan Publishers Limited, part of Springer Nature. 2018
– notice: COPYRIGHT 2018 Nature Publishing Group
– notice: Copyright Nature Publishing Group Jan 2018
DBID CGR
CUY
CVF
ECM
EIF
NPM
AAYXX
CITATION
3V.
7QL
7RV
7T5
7T7
7TM
7TO
7U9
7X7
7XB
88E
8AO
8C1
8FD
8FE
8FH
8FI
8FJ
8FK
ABUWG
AFKRA
AZQEC
BBNVY
BENPR
BHPHI
C1K
CCPQU
DWQXO
FR3
FYUFA
GHDGH
GNUQQ
H94
HCIFZ
K9.
KB0
LK8
M0S
M1P
M7N
M7P
NAPCQ
P64
PQEST
PQQKQ
PQUKI
PRINS
7X8
DOI 10.1038/leu.2017.203
DatabaseName Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
CrossRef
ProQuest Central (Corporate)
Bacteriology Abstracts (Microbiology B)
Nursing & Allied Health Database
Immunology Abstracts
Industrial and Applied Microbiology Abstracts (Microbiology A)
Nucleic Acids Abstracts
Oncogenes and Growth Factors Abstracts
Virology and AIDS Abstracts
Health & Medical Collection
ProQuest Central (purchase pre-March 2016)
Medical Database (Alumni Edition)
ProQuest Pharma Collection
Public Health Database
Technology Research Database
ProQuest SciTech Collection
ProQuest Natural Science Collection
Hospital Premium Collection
Hospital Premium Collection (Alumni Edition)
ProQuest Central (Alumni) (purchase pre-March 2016)
ProQuest Central (Alumni)
ProQuest Central UK/Ireland
ProQuest Central Essentials
Biological Science Collection
ProQuest Central
Natural Science Collection
Environmental Sciences and Pollution Management
ProQuest One Community College
ProQuest Central Korea
Engineering Research Database
Health Research Premium Collection
Health Research Premium Collection (Alumni)
ProQuest Central Student
AIDS and Cancer Research Abstracts
SciTech Premium Collection (Proquest) (PQ_SDU_P3)
ProQuest Health & Medical Complete (Alumni)
Nursing & Allied Health Database (Alumni Edition)
ProQuest Biological Science Collection
Health & Medical Collection (Alumni Edition)
Medical Database
Algology Mycology and Protozoology Abstracts (Microbiology C)
Biological Science Database
Nursing & Allied Health Premium
Biotechnology and BioEngineering Abstracts
ProQuest One Academic Eastern Edition (DO NOT USE)
ProQuest One Academic
ProQuest One Academic UKI Edition
ProQuest Central China
MEDLINE - Academic
DatabaseTitle MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
CrossRef
ProQuest Central Student
Oncogenes and Growth Factors Abstracts
Technology Research Database
ProQuest Central Essentials
Nucleic Acids Abstracts
ProQuest Health & Medical Complete (Alumni)
ProQuest Central (Alumni Edition)
SciTech Premium Collection
ProQuest One Community College
ProQuest Natural Science Collection
ProQuest Pharma Collection
ProQuest Central China
Environmental Sciences and Pollution Management
ProQuest Central
Health Research Premium Collection
Health and Medicine Complete (Alumni Edition)
Natural Science Collection
ProQuest Central Korea
Bacteriology Abstracts (Microbiology B)
Algology Mycology and Protozoology Abstracts (Microbiology C)
Biological Science Collection
AIDS and Cancer Research Abstracts
Industrial and Applied Microbiology Abstracts (Microbiology A)
ProQuest Medical Library (Alumni)
ProQuest Public Health
Virology and AIDS Abstracts
ProQuest Biological Science Collection
ProQuest One Academic Eastern Edition
ProQuest Nursing & Allied Health Source
ProQuest Hospital Collection
Health Research Premium Collection (Alumni)
Biological Science Database
ProQuest SciTech Collection
ProQuest Hospital Collection (Alumni)
Biotechnology and BioEngineering Abstracts
Nursing & Allied Health Premium
ProQuest Health & Medical Complete
ProQuest Medical Library
ProQuest One Academic UKI Edition
Immunology Abstracts
ProQuest Nursing & Allied Health Source (Alumni)
Engineering Research Database
ProQuest One Academic
ProQuest Central (Alumni)
MEDLINE - Academic
DatabaseTitleList ProQuest Central Student




MEDLINE
MEDLINE - Academic
Database_xml – sequence: 1
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 2
  dbid: EIF
  name: MEDLINE
  url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search
  sourceTypes: Index Database
– sequence: 3
  dbid: BENPR
  name: ProQuest Central
  url: https://www.proquest.com/central
  sourceTypes: Aggregation Database
DeliveryMethod fulltext_linktorsrc
Discipline Medicine
EISSN 1476-5551
EndPage 101
ExternalDocumentID A522178854
10_1038_leu_2017_203
28659618
Genre Research Support, Non-U.S. Gov't
Journal Article
GroupedDBID ---
-Q-
.55
.XZ
0R~
29L
2WC
36B
39C
3V.
4.4
406
53G
5GY
5RE
70F
7RV
7X7
88E
8AO
8C1
8FI
8FJ
8R4
8R5
AACDK
AANZL
AAQQT
AASDW
AASML
AATNV
AAWBL
AAWTL
AAZLF
ABAKF
ABAWZ
ABDBF
ABJNI
ABLJU
ABOCM
ABUWG
ABZZP
ACAOD
ACGFO
ACGFS
ACKTT
ACMJI
ACPRK
ACRQY
ACZOJ
ADBBV
ADHDB
AEFQL
AEJRE
AEMSY
AENEX
AEVLU
AEXYK
AFBBN
AFFNX
AFKRA
AFRAH
AFSHS
AGAYW
AGEZK
AGHAI
AGQEE
AHMBA
AHSBF
AIGIU
AILAN
AJRNO
ALFFA
ALIPV
ALMA_UNASSIGNED_HOLDINGS
AMYLF
ASPBG
AVWKF
AXYYD
AZFZN
B0M
BAWUL
BBNVY
BENPR
BHPHI
BKEYQ
BKKNO
BPHCQ
BVXVI
CAG
CCPQU
COF
CS3
DIK
DNIVK
DPUIP
DU5
E3Z
EAD
EAP
EBC
EBD
EBLON
EBS
EBX
EE.
EIOEI
EJD
EMB
EMK
EMOBN
EPL
ESX
EX3
F5P
FDQFY
FEDTE
FERAY
FIGPU
FIZPM
FSGXE
FYUFA
HCIFZ
HMCUK
HVGLF
HZ~
IAO
IH2
IHR
IHW
INH
INR
ITC
IWAJR
JSO
JZLTJ
KQ8
LGEZI
LOTEE
M1P
M7P
N9A
NADUK
NAO
NAPCQ
NQJWS
NXXTH
O9-
OK1
OVD
P2P
P6G
PQQKQ
PROAC
PSQYO
Q2X
RNS
RNT
RNTTT
SNX
SNYQT
SOHCF
SRMVM
SV3
SWTZT
TAOOD
TBHMF
TDRGL
TEORI
TR2
TSG
TUS
UDS
UKHRP
WOW
X7M
Y6R
ZGI
ZXP
~8M
AAYZH
CGR
CUY
CVF
ECM
EIF
NPM
AAYXX
CITATION
AADWK
AAYFA
AAYJO
ABGIJ
ACBMV
ACBRV
ACBYP
ACIGE
ACTTH
ACVWB
ADMDM
ADQMX
ADYYL
AEDAW
AEFTE
AFNRJ
AGGBP
AHGBK
AJCLW
AJDOV
AMRJV
NYICJ
ZA5
7QL
7T5
7T7
7TM
7TO
7U9
7XB
8FD
8FE
8FH
8FK
AZQEC
C1K
DWQXO
FR3
GNUQQ
H94
K9.
LK8
M7N
P64
PQEST
PQUKI
PRINS
7X8
ID FETCH-LOGICAL-c455t-4b19f5f2047d233475c6d9d1481926c8e3df689a948ef525b768bacdf47c837e3
IEDL.DBID BENPR
ISSN 0887-6924
IngestDate Fri Oct 25 06:31:15 EDT 2024
Thu Oct 10 22:24:13 EDT 2024
Thu Feb 22 23:29:52 EST 2024
Fri Feb 02 04:18:37 EST 2024
Tue Aug 20 22:03:08 EDT 2024
Fri Aug 23 03:20:30 EDT 2024
Wed Oct 16 00:50:23 EDT 2024
Fri Oct 11 20:47:48 EDT 2024
IsPeerReviewed true
IsScholarly true
Issue 1
Language English
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c455t-4b19f5f2047d233475c6d9d1481926c8e3df689a948ef525b768bacdf47c837e3
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ORCID 0000-0002-1194-6614
PMID 28659618
PQID 1986186071
PQPubID 30521
PageCount 10
ParticipantIDs proquest_miscellaneous_1914846212
proquest_journals_1986186071
gale_infotracmisc_A522178854
gale_infotracacademiconefile_A522178854
gale_healthsolutions_A522178854
crossref_primary_10_1038_leu_2017_203
pubmed_primary_28659618
springer_journals_10_1038_leu_2017_203
PublicationCentury 2000
PublicationDate 2018-01-01
PublicationDateYYYYMMDD 2018-01-01
PublicationDate_xml – month: 01
  year: 2018
  text: 2018-01-01
  day: 01
PublicationDecade 2010
PublicationPlace London
PublicationPlace_xml – name: London
– name: England
PublicationTitle Leukemia
PublicationTitleAbbrev Leukemia
PublicationTitleAlternate Leukemia
PublicationYear 2018
Publisher Nature Publishing Group UK
Nature Publishing Group
Publisher_xml – name: Nature Publishing Group UK
– name: Nature Publishing Group
References Lam, Wright, Davis, Lenz, Farinha, Dang (CR37) 2008; 111
Gunawardana, Chan, Telenius, Woolcock, Kridel, Tan (CR47) 2014; 46
Logan, Jordan-Williams, Poston, Liao, Taparowsky (CR21) 2012; 3
Atsaves, Lekakis, Drakos, Leventaki, Ghaderi, Baltatzis (CR39) 2014; 167
Lamprecht, Kreher, Anagnostopoulos, Johrens, Monteleone, Jundt (CR45) 2008; 112
Chiarle, Simmons, Cai, Dhall, Zamo, Raz (CR50) 2005; 11
Salipante, Adey, Thomas, Lee, Liu, Kumar (CR41) 2016; 55
Li, Spolski, Liao, Wang, Murphy, Murphy (CR28) 2012; 490
Scheeren, Diehl, Smit, Beaumont, Naspetti, Bende (CR46) 2008; 111
Hartmann, Martin-Subero, Gesk, Husken, Giefing, Nagel (CR40) 2008; 93
Eferl, Wagner (CR8) 2003; 3
Rui, Emre, Kruhlak, Chung, Steidl, Slack (CR34) 2010; 18
Rodig, Ouyang, Juszczynski, Currie, Law, Neuberg (CR12) 2008; 14
Dominguez-Sola, Victora, Ying, Phan, Saito, Nussenzweig (CR31) 2012; 13
Rui, Drennan, Ceribelli, Zhu, Wright, Huang (CR53) 2016; 113
Watanabe, Sasaki, Itoh, Higashihara, Umezawa, Kadin (CR27) 2005; 65
Chisholm, Bangs, Bacchi, Molina-Kirsch, Cherry, Natkunam (CR33) 2015; 39
Küppers, Rajewsky, Zhao, Simons, Laumann, Fischer (CR3) 1994; 91
Weniger, Melzner, Menz, Wegener, Bucur, Dorsch (CR49) 2006; 25
Laimer, Dolznig, Kollmann, Vesely, Schlederer, Merkel (CR11) 2012; 18
Ngo, Young, Schmitz, Jhavar, Xiao, Lim (CR52) 2011; 470
Piva, Agnelli, Pellegrino, Todoerti, Grosso, Tamagno (CR17) 2010; 28
Drakos, Leventaki, Schlette, Jones, Lin, Medeiros (CR9) 2007; 31
Watanabe, Ogawa, Ito, Higashihara, Kadin, Abraham (CR26) 2003; 163
Liu, Iqbal, Teruya-Feldstein, Shen, Dabrowska, Dybkaer (CR44) 2013; 122
Feys, Poppe, De Preter, Van Roy, Verhasselt, De Paepe (CR42) 2007; 92
Ding, Yu, Yu, Mendez, Shaknovich, Zhang (CR36) 2008; 111
Mathas, Hinz, Anagnostopoulos, Krappmann, Lietz, Jundt (CR4) 2002; 21
Seitz, Butzhammer, Hirsch, Hecht, Gutgemann, Ehlers (CR29) 2011; 6
Hapgood, Savage (CR6) 2015; 126
Weilemann, Grau, Erdmann, Merkel, Sobhiafshar, Anagnostopoulos (CR30) 2015; 125
Stein, Mason, Gerdes, O'Connor, Wainscoat, Pallesen (CR7) 1985; 66
Brune, Tiacci, Pfeil, Doring, Eckerle, van Noesel (CR14) 2008; 205
Tiacci, Döring, Brune, van Noesel, Klapper, Mechtersheimer (CR23) 2012; 120
Carbone, Gloghini, Aldinucci, Gattei, Dalla-Favera, Gaidano (CR55) 2002; 117
Zamo, Chiarle, Piva, Howes, Fan, Chilosi (CR51) 2002; 21
Hildner, Edelson, Purtha, Diamond, Matsushita, Kohyama (CR18) 2008; 322
Kreher, Bouhlel, Cauchy, Lamprecht, Li, Grau (CR54) 2014; 111
Crescenzo, Abate, Lasorsa, Tabbo, Gaudiano, Chiesa (CR35) 2015; 27
Schwering, Bräuninger, Distler, Jesdinsky, Diehl, Hansmann (CR16) 2003; 9
Underhill, George, Bremer, Kansas (CR25) 2003; 101
Skinnider, Elia, Gascoyne, Patterson, Trümper, Kapp (CR38) 2002; 99
Shaffer, Emre, Lamy, Ngo, Wright, Xiao (CR56) 2008; 454
Yang, Shaffer, Emre, Ceribelli, Zhang, Wright (CR57) 2012; 21
Green, Rodig, Juszczynski, Ouyang, Sinha, O'Donnell (CR13) 2012; 18
Shaffer, Staudt (CR58) 2012; 13
Rosenwald, Wright, Leroy, Yu, Gaulard, Gascoyne (CR15) 2003; 198
Joos, Küpper, Ohl, von Bonin, Mechtersheimer, Bentz (CR48) 2000; 60
Murphy, Tussiwand, Murphy (CR19) 2013; 13
Iavarone, Catania, Marinissen, Visconti, Acunzo, Tarantino (CR32) 2003; 278
Rassidakis, Thomaides, Atwell, Ford, Jones, Claret (CR10) 2005; 18
Weber, Bartsch, Stocking, Fehse (CR22) 2008; 16
Steidl, Diepstra, Lee, Chan, Farinha, Tan (CR24) 2012; 120
Salaverria, Bea, Lopez-Guillermo, Lespinet, Pinyol, Burkhardt (CR43) 2008; 140
Schmitz, Stanelle, Hansmann, Küppers (CR1) 2009; 4
Kanzler, Küppers, Hansmann, Rajewsky (CR2) 1996; 184
Tussiwand, Lee, Murphy, Mashayekhi, Kc, Albring (CR20) 2012; 490
Eckerle, Brune, Doring, Tiacci, Bohle, Sundstrom (CR5) 2009; 23
22271878 - Clin Cancer Res. 2012 Mar 15;18(6):1611-8
22955918 - Blood. 2012 Oct 25;120(17):3530-40
15895073 - Nat Med. 2005 Jun;11(6):623-9
22698399 - Cancer Cell. 2012 Jun 12;21(6):723-37
25869285 - Blood. 2015 Jul 2;126(1):17-25
23064464 - Nat Med. 2012 Nov;18(11):1699-704
21156283 - Cancer Cell. 2010 Dec 14;18(6):590-605
18519761 - Clin Cancer Res. 2008 Jun 1;14(11):3338-44
11972519 - Br J Haematol. 2002 May;117(2):366-72
25581730 - Am J Surg Pathol. 2015 Mar;39(3):294-303
12875982 - Am J Pathol. 2003 Aug;163(2):633-41
8879220 - J Exp Med. 1996 Oct 1;184(4):1495-505
14668816 - Nat Rev Cancer. 2003 Nov;3(11):859-68
24531327 - Nat Genet. 2014 Apr;46(4):329-35
17606441 - Haematologica. 2007 Jul;92(7):913-20
17951530 - Blood. 2008 Feb 1;111(3):1515-23
12975453 - J Exp Med. 2003 Sep 15;198(6):851-62
7971992 - Proc Natl Acad Sci U S A. 1994 Nov 8;91(23):10962-6
16532038 - Oncogene. 2006 Apr 27;25(18):2679-84
21179087 - Nature. 2011 Feb 3;470(7332):115-9
15920551 - Mod Pathol. 2005 Oct;18(10):1365-70
22992524 - Nature. 2012 Oct 25;490(7421):502-7
23001145 - Nat Immunol. 2012 Nov;13(11):1083-91
3876124 - Blood. 1985 Oct;66(4):848-58
22992523 - Nature. 2012 Oct 25;490(7421):543-6
25359993 - Blood. 2015 Jan 1;125(1):124-32
26650888 - Genes Chromosomes Cancer. 2016 Mar;55(3):278-87
10676635 - Cancer Res. 2000 Feb 1;60(3):549-52
18362927 - Mol Ther. 2008 Apr;16(4):698-706
27799566 - Proc Natl Acad Sci U S A. 2016 Nov 15;113(46):E7260-E7267
23801630 - Blood. 2013 Sep 19;122(12):2083-92
18275429 - Br J Haematol. 2008 Mar;140(5):516-26
16140928 - Cancer Res. 2005 Sep 1;65(17):7628-34
23787991 - Nat Rev Immunol. 2013 Jul;13(7):499-509
12865944 - Mol Med. 2003 Mar-Apr;9(3-4):85-95
12543863 - Blood. 2003 May 15;101(10):4013-21
22592317 - Cell Death Dis. 2012 May 17;3:e310
18641027 - Haematologica. 2008 Sep;93(9):1318-26
19400691 - Annu Rev Pathol. 2009;4:151-74
19657361 - Leukemia. 2009 Nov;23(11):2129-38
25288773 - Proc Natl Acad Sci U S A. 2014 Oct 21;111(42):E4513-22
14523011 - J Biol Chem. 2003 Dec 12;278(50):50024-30
18160665 - Blood. 2008 Apr 1;111(7):3701-13
18794340 - J Exp Med. 2008 Sep 29;205(10):2251-68
18296629 - Blood. 2008 May 1;111(9):4706-15
12145210 - EMBO J. 2002 Aug 1;21(15):4104-13
20159827 - J Clin Oncol. 2010 Mar 20;28(9):1583-90
18568025 - Nature. 2008 Jul 10;454(7201):226-31
18684866 - Blood. 2008 Oct 15;112(8):3339-47
22102868 - PLoS One. 2011;6(11):e26837
22955914 - Blood. 2012 Nov 29;120(23 ):4609-20
25873174 - Cancer Cell. 2015 Apr 13;27(4):516-32
19008445 - Science. 2008 Nov 14;322(5904):1097-100
23080195 - Nat Immunol. 2012 Nov;13(11):1029-31
25145835 - Br J Haematol. 2014 Nov;167(4):514-23
17325487 - Am J Surg Pathol. 2007 Mar;31(3):447-53
11850821 - Oncogene. 2002 Feb 7;21(7):1038-47
11781246 - Blood. 2002 Jan 15;99(2):618-26
V Atsaves (BFleu2017203_CR39) 2014; 167
K Hildner (BFleu2017203_CR18) 2008; 322
D Dominguez-Sola (BFleu2017203_CR31) 2012; 13
L Rui (BFleu2017203_CR53) 2016; 113
MR Logan (BFleu2017203_CR21) 2012; 3
S Mathas (BFleu2017203_CR4) 2002; 21
S Eckerle (BFleu2017203_CR5) 2009; 23
E Drakos (BFleu2017203_CR9) 2007; 31
S Joos (BFleu2017203_CR48) 2000; 60
V Seitz (BFleu2017203_CR29) 2011; 6
D Laimer (BFleu2017203_CR11) 2012; 18
C Liu (BFleu2017203_CR44) 2013; 122
AL Shaffer (BFleu2017203_CR56) 2008; 454
FA Scheeren (BFleu2017203_CR46) 2008; 111
R Piva (BFleu2017203_CR17) 2010; 28
G Hapgood (BFleu2017203_CR6) 2015; 126
MR Green (BFleu2017203_CR13) 2012; 18
GZ Rassidakis (BFleu2017203_CR10) 2005; 18
R Chiarle (BFleu2017203_CR50) 2005; 11
R Schmitz (BFleu2017203_CR1) 2009; 4
SJ Salipante (BFleu2017203_CR41) 2016; 55
AL Shaffer (BFleu2017203_CR58) 2012; 13
R Eferl (BFleu2017203_CR8) 2003; 3
R Tussiwand (BFleu2017203_CR20) 2012; 490
BB Ding (BFleu2017203_CR36) 2008; 111
SJ Rodig (BFleu2017203_CR12) 2008; 14
M Watanabe (BFleu2017203_CR27) 2005; 65
P Li (BFleu2017203_CR28) 2012; 490
S Hartmann (BFleu2017203_CR40) 2008; 93
S Kreher (BFleu2017203_CR54) 2014; 111
A Zamo (BFleu2017203_CR51) 2002; 21
E Tiacci (BFleu2017203_CR23) 2012; 120
KM Chisholm (BFleu2017203_CR33) 2015; 39
BF Skinnider (BFleu2017203_CR38) 2002; 99
R Küppers (BFleu2017203_CR3) 1994; 91
L Rui (BFleu2017203_CR34) 2010; 18
J Gunawardana (BFleu2017203_CR47) 2014; 46
M Watanabe (BFleu2017203_CR26) 2003; 163
Y Yang (BFleu2017203_CR57) 2012; 21
T Feys (BFleu2017203_CR42) 2007; 92
H Stein (BFleu2017203_CR7) 1985; 66
C Iavarone (BFleu2017203_CR32) 2003; 278
B Lamprecht (BFleu2017203_CR45) 2008; 112
GH Underhill (BFleu2017203_CR25) 2003; 101
MA Weniger (BFleu2017203_CR49) 2006; 25
I Salaverria (BFleu2017203_CR43) 2008; 140
A Rosenwald (BFleu2017203_CR15) 2003; 198
A Weilemann (BFleu2017203_CR30) 2015; 125
K Weber (BFleu2017203_CR22) 2008; 16
LT Lam (BFleu2017203_CR37) 2008; 111
VN Ngo (BFleu2017203_CR52) 2011; 470
A Carbone (BFleu2017203_CR55) 2002; 117
H Kanzler (BFleu2017203_CR2) 1996; 184
I Schwering (BFleu2017203_CR16) 2003; 9
V Brune (BFleu2017203_CR14) 2008; 205
C Steidl (BFleu2017203_CR24) 2012; 120
TL Murphy (BFleu2017203_CR19) 2013; 13
R Crescenzo (BFleu2017203_CR35) 2015; 27
References_xml – volume: 11
  start-page: 623
  year: 2005
  end-page: 629
  ident: CR50
  article-title: Stat3 is required for ALK-mediated lymphomagenesis and provides a possible therapeutic target
  publication-title: Nat Med
  doi: 10.1038/nm1249
  contributor:
    fullname: Raz
– volume: 23
  start-page: 2129
  year: 2009
  end-page: 2138
  ident: CR5
  article-title: Gene expression profiling of isolated tumour cells from anaplastic large cell lymphomas: insights into its cellular origin, pathogenesis and relation to Hodgkin lymphoma
  publication-title: Leukemia
  doi: 10.1038/leu.2009.161
  contributor:
    fullname: Sundstrom
– volume: 4
  start-page: 151
  year: 2009
  end-page: 174
  ident: CR1
  article-title: Pathogenesis of classical and lymphocyte-predominant Hodgkin lymphoma
  publication-title: Annu Rev Pathol
  doi: 10.1146/annurev.pathol.4.110807.092209
  contributor:
    fullname: Küppers
– volume: 120
  start-page: 4609
  year: 2012
  end-page: 4620
  ident: CR23
  article-title: Analyzing primary Hodgkin and Reed-Sternberg cells to capture the molecular and cellular pathogenesis of classical Hodgkin lymphoma
  publication-title: Blood
  doi: 10.1182/blood-2012-05-428896
  contributor:
    fullname: Mechtersheimer
– volume: 122
  start-page: 2083
  year: 2013
  end-page: 2092
  ident: CR44
  article-title: MicroRNA expression profiling identifies molecular signatures associated with anaplastic large cell lymphoma
  publication-title: Blood
  doi: 10.1182/blood-2012-08-447375
  contributor:
    fullname: Dybkaer
– volume: 111
  start-page: E4513
  year: 2014
  end-page: E4522
  ident: CR54
  article-title: Mapping of transcription factor motifs in active chromatin identifies IRF5 as key regulator in classical Hodgkin lymphoma
  publication-title: Proc Natl Acad Sci USA
  doi: 10.1073/pnas.1406985111
  contributor:
    fullname: Grau
– volume: 163
  start-page: 633
  year: 2003
  end-page: 641
  ident: CR26
  article-title: AP-1 mediated relief of repressive activity of the CD30 promoter microsatellite in Hodgkin and Reed-Sternberg cells
  publication-title: Am J Pathol
  doi: 10.1016/S0002-9440(10)63690-5
  contributor:
    fullname: Abraham
– volume: 120
  start-page: 3530
  year: 2012
  end-page: 3540
  ident: CR24
  article-title: Gene expression profiling of microdissected Hodgkin Reed-Sternberg cells correlates with treatment outcome in classical Hodgkin lymphoma
  publication-title: Blood
  doi: 10.1182/blood-2012-06-439570
  contributor:
    fullname: Tan
– volume: 92
  start-page: 913
  year: 2007
  end-page: 920
  ident: CR42
  article-title: A detailed inventory of DNA copy number alterations in four commonly used Hodgkin's lymphoma cell lines
  publication-title: Haematologica
  doi: 10.3324/haematol.11073
  contributor:
    fullname: De Paepe
– volume: 13
  start-page: 499
  year: 2013
  end-page: 509
  ident: CR19
  article-title: Specificity through cooperation: BATF-IRF interactions control immune-regulatory networks
  publication-title: Nat Rev Immunol
  doi: 10.1038/nri3470
  contributor:
    fullname: Murphy
– volume: 101
  start-page: 4013
  year: 2003
  end-page: 4021
  ident: CR25
  article-title: Gene expression profiling reveals a highly specialized genetic program of plasma cells
  publication-title: Blood
  doi: 10.1182/blood-2002-08-2673
  contributor:
    fullname: Kansas
– volume: 490
  start-page: 502
  year: 2012
  end-page: 507
  ident: CR20
  article-title: Compensatory dendritic cell development mediated by BATF-IRF interactions
  publication-title: Nature
  doi: 10.1038/nature11531
  contributor:
    fullname: Albring
– volume: 205
  start-page: 2251
  year: 2008
  end-page: 2268
  ident: CR14
  article-title: Origin and pathogenesis of nodular lymphocyte-predominant Hodgkin lymphoma as revealed by global gene expression analysis
  publication-title: J Exp Med
  doi: 10.1084/jem.20080809
  contributor:
    fullname: van Noesel
– volume: 9
  start-page: 85
  year: 2003
  end-page: 95
  ident: CR16
  article-title: Profiling of Hodgkin's lymphoma cell line L1236 and germinal center B cells: identification of Hodgkin's lymphoma-specific genes
  publication-title: Mol Med
  doi: 10.1007/BF03402041
  contributor:
    fullname: Hansmann
– volume: 111
  start-page: 4706
  year: 2008
  end-page: 4715
  ident: CR46
  article-title: IL-21 is expressed in Hodgkin lymphoma and activates STAT5; evidence that activated STAT5 is required for Hodgkin lymphomagenesis
  publication-title: Blood
  doi: 10.1182/blood-2007-08-105643
  contributor:
    fullname: Bende
– volume: 6
  start-page: e26837
  year: 2011
  ident: CR29
  article-title: Deep sequencing of MYC DNA-binding sites in Burkitt lymphoma
  publication-title: PLoS ONE
  doi: 10.1371/journal.pone.0026837
  contributor:
    fullname: Ehlers
– volume: 113
  start-page: E7260
  year: 2016
  end-page: E7267
  ident: CR53
  article-title: Epigenetic gene regulation by Janus kinase 1 in diffuse large B-cell lymphoma
  publication-title: Proc Natl Acad Sci USA
  doi: 10.1073/pnas.1610970113
  contributor:
    fullname: Huang
– volume: 18
  start-page: 1611
  year: 2012
  end-page: 1618
  ident: CR13
  article-title: Constitutive AP-1 activity and EBV infection induce PD-L1 in Hodgkin lymphomas and posttransplant lymphoproliferative disorders: implications for targeted therapy
  publication-title: Clin Cancer Res
  doi: 10.1158/1078-0432.CCR-11-1942
  contributor:
    fullname: O'Donnell
– volume: 278
  start-page: 50024
  year: 2003
  end-page: 50030
  ident: CR32
  article-title: The platelet-derived growth factor controls c-myc expression through a JNK- and AP-1-dependent signaling pathway
  publication-title: J Biol Chem
  doi: 10.1074/jbc.M308617200
  contributor:
    fullname: Tarantino
– volume: 25
  start-page: 2679
  year: 2006
  end-page: 2684
  ident: CR49
  article-title: Mutations of the tumor suppressor gene SOCS-1 in classical Hodgkin lymphoma are frequent and associated with nuclear phospho-STAT5 accumulation
  publication-title: Oncogene
  doi: 10.1038/sj.onc.1209151
  contributor:
    fullname: Dorsch
– volume: 39
  start-page: 294
  year: 2015
  end-page: 303
  ident: CR33
  article-title: Expression profiles of MYC protein and MYC gene rearrangement in lymphomas
  publication-title: Am J Surg Pathol
  doi: 10.1097/PAS.0000000000000365
  contributor:
    fullname: Natkunam
– volume: 3
  start-page: e310
  year: 2012
  ident: CR21
  article-title: Overexpression of Batf induces an apoptotic defect and an associated lymphoproliferative disorder in mice
  publication-title: Cell Death Dis
  doi: 10.1038/cddis.2012.49
  contributor:
    fullname: Taparowsky
– volume: 470
  start-page: 115
  year: 2011
  end-page: 119
  ident: CR52
  article-title: Oncogenically active MYD88 mutations in human lymphoma
  publication-title: Nature
  doi: 10.1038/nature09671
  contributor:
    fullname: Lim
– volume: 490
  start-page: 543
  year: 2012
  end-page: 546
  ident: CR28
  article-title: BATF-JUN is critical for IRF4-mediated transcription in T cells
  publication-title: Nature
  doi: 10.1038/nature11530
  contributor:
    fullname: Murphy
– volume: 184
  start-page: 1495
  year: 1996
  end-page: 1505
  ident: CR2
  article-title: Hodgkin and Reed-Sternberg cells in Hodgkin's disease represent the outgrowth of a dominant tumor clone derived from (crippled) germinal center B cells
  publication-title: J Exp Med
  doi: 10.1084/jem.184.4.1495
  contributor:
    fullname: Rajewsky
– volume: 28
  start-page: 1583
  year: 2010
  end-page: 1590
  ident: CR17
  article-title: Gene expression profiling uncovers molecular classifiers for the recognition of anaplastic large-cell lymphoma within peripheral T-cell neoplasms
  publication-title: J Clin Oncol
  doi: 10.1200/JCO.2008.20.9759
  contributor:
    fullname: Tamagno
– volume: 60
  start-page: 549
  year: 2000
  end-page: 552
  ident: CR48
  article-title: Genomic imbalances including amplification of the tyrosine kinase gene JAK2 in CD30+ Hodgkin cells
  publication-title: Cancer Res
  contributor:
    fullname: Bentz
– volume: 126
  start-page: 17
  year: 2015
  end-page: 25
  ident: CR6
  article-title: The biology and management of systemic anaplastic large cell lymphoma
  publication-title: Blood
  doi: 10.1182/blood-2014-10-567461
  contributor:
    fullname: Savage
– volume: 18
  start-page: 1699
  year: 2012
  end-page: 1704
  ident: CR11
  article-title: PDGFR blockade is a rational and effective therapy for NPM-ALK-driven lymphomas
  publication-title: Nat Med
  doi: 10.1038/nm.2966
  contributor:
    fullname: Merkel
– volume: 125
  start-page: 124
  year: 2015
  end-page: 132
  ident: CR30
  article-title: Essential role of IRF4 and MYC signaling for survival of anaplastic large cell lymphoma
  publication-title: Blood
  doi: 10.1182/blood-2014-08-594507
  contributor:
    fullname: Anagnostopoulos
– volume: 21
  start-page: 723
  year: 2012
  end-page: 737
  ident: CR57
  article-title: Exploiting synthetic lethality for the therapy of ABC diffuse large B cell lymphoma
  publication-title: Cancer Cell
  doi: 10.1016/j.ccr.2012.05.024
  contributor:
    fullname: Wright
– volume: 112
  start-page: 3339
  year: 2008
  end-page: 3347
  ident: CR45
  article-title: Aberrant expression of the Th2 cytokine IL-21 in Hodgkin lymphoma cells regulates STAT3 signaling and attracts Treg cells via regulation of MIP-3alpha
  publication-title: Blood
  doi: 10.1182/blood-2008-01-134783
  contributor:
    fullname: Jundt
– volume: 66
  start-page: 848
  year: 1985
  end-page: 858
  ident: CR7
  article-title: The expression of the Hodgkin's disease associated antigen Ki-1 in reactive and neoplastic lymphoid tissue: evidence that Reed-Sternberg cells and histiocytic malignancies are derived from activated lymphoid cells
  publication-title: Blood
  contributor:
    fullname: Pallesen
– volume: 18
  start-page: 1365
  year: 2005
  end-page: 1370
  ident: CR10
  article-title: JunB expression is a common feature of CD30+ lymphomas and lymphomatoid papulosis
  publication-title: Mod Pathol
  doi: 10.1038/modpathol.3800419
  contributor:
    fullname: Claret
– volume: 111
  start-page: 3701
  year: 2008
  end-page: 3713
  ident: CR37
  article-title: Cooperative signaling through the signal transducer and activator of transcription 3 and nuclear factor-{kappa}B pathways in subtypes of diffuse large B-cell lymphoma
  publication-title: Blood
  doi: 10.1182/blood-2007-09-111948
  contributor:
    fullname: Dang
– volume: 13
  start-page: 1029
  year: 2012
  end-page: 1031
  ident: CR58
  article-title: The case of the missing c-Myc
  publication-title: Nat Immunol
  doi: 10.1038/ni.2455
  contributor:
    fullname: Staudt
– volume: 21
  start-page: 1038
  year: 2002
  end-page: 1047
  ident: CR51
  article-title: Anaplastic lymphoma kinase (ALK) activates Stat3 and protects hematopoietic cells from cell death
  publication-title: Oncogene
  doi: 10.1038/sj.onc.1205152
  contributor:
    fullname: Chilosi
– volume: 21
  start-page: 4104
  year: 2002
  end-page: 4113
  ident: CR4
  article-title: Aberrantly expressed c-Jun and JunB are a hallmark of Hodgkin lymphoma cells, stimulate proliferation and synergize with NF-kappa B
  publication-title: EMBO J
  doi: 10.1093/emboj/cdf389
  contributor:
    fullname: Jundt
– volume: 14
  start-page: 3338
  year: 2008
  end-page: 3344
  ident: CR12
  article-title: AP1-dependent galectin-1 expression delineates classical hodgkin and anaplastic large cell lymphomas from other lymphoid malignancies with shared molecular features
  publication-title: Clin Cancer Res
  doi: 10.1158/1078-0432.CCR-07-4709
  contributor:
    fullname: Neuberg
– volume: 3
  start-page: 859
  year: 2003
  end-page: 868
  ident: CR8
  article-title: AP-1: a double-edged sword in tumorigenesis
  publication-title: Nat Rev Cancer
  doi: 10.1038/nrc1209
  contributor:
    fullname: Wagner
– volume: 454
  start-page: 226
  year: 2008
  end-page: 231
  ident: CR56
  article-title: IRF4 addiction in multiple myeloma
  publication-title: Nature
  doi: 10.1038/nature07064
  contributor:
    fullname: Xiao
– volume: 27
  start-page: 516
  year: 2015
  end-page: 532
  ident: CR35
  article-title: Convergent mutations and kinase fusions lead to oncogenic STAT3 activation in anaplastic large cell lymphoma
  publication-title: Cancer Cell
  doi: 10.1016/j.ccell.2015.03.006
  contributor:
    fullname: Chiesa
– volume: 93
  start-page: 1318
  year: 2008
  end-page: 1326
  ident: CR40
  article-title: Detection of genomic imbalances in microdissected Hodgkin and Reed-Sternberg cells of classical Hodgkin's lymphoma by array-based comparative genomic hybridization
  publication-title: Haematologica
  doi: 10.3324/haematol.12875
  contributor:
    fullname: Nagel
– volume: 140
  start-page: 516
  year: 2008
  end-page: 526
  ident: CR43
  article-title: Genomic profiling reveals different genetic aberrations in systemic ALK-positive and ALK-negative anaplastic large cell lymphomas
  publication-title: Br J Haematol
  doi: 10.1111/j.1365-2141.2007.06924.x
  contributor:
    fullname: Burkhardt
– volume: 99
  start-page: 618
  year: 2002
  end-page: 626
  ident: CR38
  article-title: Signal transducer and activator of transcription 6 is frequently activated in Hodgkin and Reed-Sternberg cells of Hodgkin lymphoma
  publication-title: Blood
  doi: 10.1182/blood.V99.2.618
  contributor:
    fullname: Kapp
– volume: 91
  start-page: 10962
  year: 1994
  end-page: 10966
  ident: CR3
  article-title: Hodgkin disease: Hodgkin and Reed-Sternberg cells picked from histological sections show clonal immunoglobulin gene rearrangements and appear to be derived from B cells at various stages of development
  publication-title: Proc Natl Acad Sci USA
  doi: 10.1073/pnas.91.23.10962
  contributor:
    fullname: Fischer
– volume: 65
  start-page: 7628
  year: 2005
  end-page: 7634
  ident: CR27
  article-title: JunB induced by constitutive CD30-extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase signaling activates the CD30 promoter in anaplastic large cell lymphoma and reed-sternberg cells of Hodgkin lymphoma
  publication-title: Cancer Res
  doi: 10.1158/0008-5472.CAN-05-0925
  contributor:
    fullname: Kadin
– volume: 167
  start-page: 514
  year: 2014
  end-page: 523
  ident: CR39
  article-title: The oncogenic JUNB/CD30 axis contributes to cell cycle deregulation in ALK+ anaplastic large cell lymphoma
  publication-title: Br J Haematol
  doi: 10.1111/bjh.13079
  contributor:
    fullname: Baltatzis
– volume: 198
  start-page: 851
  year: 2003
  end-page: 862
  ident: CR15
  article-title: Molecular diagnosis of primary mediastinal B cell lymphoma identifies a clinically favorable subgroup of diffuse large B cell lymphoma related to Hodgkin lymphoma
  publication-title: J Exp Med
  doi: 10.1084/jem.20031074
  contributor:
    fullname: Gascoyne
– volume: 322
  start-page: 1097
  year: 2008
  end-page: 1100
  ident: CR18
  article-title: Batf3 deficiency reveals a critical role for CD8alpha+ dendritic cells in cytotoxic T cell immunity
  publication-title: Science
  doi: 10.1126/science.1164206
  contributor:
    fullname: Kohyama
– volume: 46
  start-page: 329
  year: 2014
  end-page: 335
  ident: CR47
  article-title: Recurrent somatic mutations of PTPN1 in primary mediastinal B cell lymphoma and Hodgkin lymphoma
  publication-title: Nat Genet
  doi: 10.1038/ng.2900
  contributor:
    fullname: Tan
– volume: 13
  start-page: 1083
  year: 2012
  end-page: 1091
  ident: CR31
  article-title: The proto-oncogene MYC is required for selection in the germinal center and cyclic reentry
  publication-title: Nat Immunol
  doi: 10.1038/ni.2428
  contributor:
    fullname: Nussenzweig
– volume: 31
  start-page: 447
  year: 2007
  end-page: 453
  ident: CR9
  article-title: c-Jun expression and activation are restricted to CD30+ lymphoproliferative disorders
  publication-title: Am J Surg Pathol
  doi: 10.1097/01.pas.0000213412.25935.e4
  contributor:
    fullname: Medeiros
– volume: 16
  start-page: 698
  year: 2008
  end-page: 706
  ident: CR22
  article-title: A multicolor panel of novel lentiviral "gene ontology" (LeGO) vectors for functional gene analysis
  publication-title: Mol Ther
  doi: 10.1038/mt.2008.6
  contributor:
    fullname: Fehse
– volume: 55
  start-page: 278
  year: 2016
  end-page: 287
  ident: CR41
  article-title: Recurrent somatic loss of TNFRSF14 in classical Hodgkin lymphoma
  publication-title: Genes Chromosomes Cancer
  doi: 10.1002/gcc.22331
  contributor:
    fullname: Kumar
– volume: 111
  start-page: 1515
  year: 2008
  end-page: 1523
  ident: CR36
  article-title: Constitutively activated STAT3 promotes cell proliferation and survival in the activated B-cell subtype of diffuse large B-cell lymphomas
  publication-title: Blood
  doi: 10.1182/blood-2007-04-087734
  contributor:
    fullname: Zhang
– volume: 117
  start-page: 366
  year: 2002
  end-page: 372
  ident: CR55
  article-title: Expression pattern of MUM1/IRF4 in the spectrum of pathology of Hodgkin's disease
  publication-title: Br J Haematol
  doi: 10.1046/j.1365-2141.2002.03456.x
  contributor:
    fullname: Gaidano
– volume: 18
  start-page: 590
  year: 2010
  end-page: 605
  ident: CR34
  article-title: Cooperative epigenetic modulation by cancer amplicon genes
  publication-title: Cancer Cell
  doi: 10.1016/j.ccr.2010.11.013
  contributor:
    fullname: Slack
– volume: 9
  start-page: 85
  year: 2003
  ident: BFleu2017203_CR16
  publication-title: Mol Med
  doi: 10.1007/BF03402041
  contributor:
    fullname: I Schwering
– volume: 18
  start-page: 590
  year: 2010
  ident: BFleu2017203_CR34
  publication-title: Cancer Cell
  doi: 10.1016/j.ccr.2010.11.013
  contributor:
    fullname: L Rui
– volume: 454
  start-page: 226
  year: 2008
  ident: BFleu2017203_CR56
  publication-title: Nature
  doi: 10.1038/nature07064
  contributor:
    fullname: AL Shaffer
– volume: 21
  start-page: 1038
  year: 2002
  ident: BFleu2017203_CR51
  publication-title: Oncogene
  doi: 10.1038/sj.onc.1205152
  contributor:
    fullname: A Zamo
– volume: 27
  start-page: 516
  year: 2015
  ident: BFleu2017203_CR35
  publication-title: Cancer Cell
  doi: 10.1016/j.ccell.2015.03.006
  contributor:
    fullname: R Crescenzo
– volume: 31
  start-page: 447
  year: 2007
  ident: BFleu2017203_CR9
  publication-title: Am J Surg Pathol
  doi: 10.1097/01.pas.0000213412.25935.e4
  contributor:
    fullname: E Drakos
– volume: 125
  start-page: 124
  year: 2015
  ident: BFleu2017203_CR30
  publication-title: Blood
  doi: 10.1182/blood-2014-08-594507
  contributor:
    fullname: A Weilemann
– volume: 46
  start-page: 329
  year: 2014
  ident: BFleu2017203_CR47
  publication-title: Nat Genet
  doi: 10.1038/ng.2900
  contributor:
    fullname: J Gunawardana
– volume: 4
  start-page: 151
  year: 2009
  ident: BFleu2017203_CR1
  publication-title: Annu Rev Pathol
  doi: 10.1146/annurev.pathol.4.110807.092209
  contributor:
    fullname: R Schmitz
– volume: 3
  start-page: e310
  year: 2012
  ident: BFleu2017203_CR21
  publication-title: Cell Death Dis
  doi: 10.1038/cddis.2012.49
  contributor:
    fullname: MR Logan
– volume: 117
  start-page: 366
  year: 2002
  ident: BFleu2017203_CR55
  publication-title: Br J Haematol
  doi: 10.1046/j.1365-2141.2002.03456.x
  contributor:
    fullname: A Carbone
– volume: 60
  start-page: 549
  year: 2000
  ident: BFleu2017203_CR48
  publication-title: Cancer Res
  contributor:
    fullname: S Joos
– volume: 111
  start-page: 3701
  year: 2008
  ident: BFleu2017203_CR37
  publication-title: Blood
  doi: 10.1182/blood-2007-09-111948
  contributor:
    fullname: LT Lam
– volume: 6
  start-page: e26837
  year: 2011
  ident: BFleu2017203_CR29
  publication-title: PLoS ONE
  doi: 10.1371/journal.pone.0026837
  contributor:
    fullname: V Seitz
– volume: 120
  start-page: 4609
  year: 2012
  ident: BFleu2017203_CR23
  publication-title: Blood
  doi: 10.1182/blood-2012-05-428896
  contributor:
    fullname: E Tiacci
– volume: 13
  start-page: 1083
  year: 2012
  ident: BFleu2017203_CR31
  publication-title: Nat Immunol
  doi: 10.1038/ni.2428
  contributor:
    fullname: D Dominguez-Sola
– volume: 11
  start-page: 623
  year: 2005
  ident: BFleu2017203_CR50
  publication-title: Nat Med
  doi: 10.1038/nm1249
  contributor:
    fullname: R Chiarle
– volume: 3
  start-page: 859
  year: 2003
  ident: BFleu2017203_CR8
  publication-title: Nat Rev Cancer
  doi: 10.1038/nrc1209
  contributor:
    fullname: R Eferl
– volume: 21
  start-page: 4104
  year: 2002
  ident: BFleu2017203_CR4
  publication-title: EMBO J
  doi: 10.1093/emboj/cdf389
  contributor:
    fullname: S Mathas
– volume: 111
  start-page: 1515
  year: 2008
  ident: BFleu2017203_CR36
  publication-title: Blood
  doi: 10.1182/blood-2007-04-087734
  contributor:
    fullname: BB Ding
– volume: 122
  start-page: 2083
  year: 2013
  ident: BFleu2017203_CR44
  publication-title: Blood
  doi: 10.1182/blood-2012-08-447375
  contributor:
    fullname: C Liu
– volume: 111
  start-page: 4706
  year: 2008
  ident: BFleu2017203_CR46
  publication-title: Blood
  doi: 10.1182/blood-2007-08-105643
  contributor:
    fullname: FA Scheeren
– volume: 91
  start-page: 10962
  year: 1994
  ident: BFleu2017203_CR3
  publication-title: Proc Natl Acad Sci USA
  doi: 10.1073/pnas.91.23.10962
  contributor:
    fullname: R Küppers
– volume: 18
  start-page: 1699
  year: 2012
  ident: BFleu2017203_CR11
  publication-title: Nat Med
  doi: 10.1038/nm.2966
  contributor:
    fullname: D Laimer
– volume: 28
  start-page: 1583
  year: 2010
  ident: BFleu2017203_CR17
  publication-title: J Clin Oncol
  doi: 10.1200/JCO.2008.20.9759
  contributor:
    fullname: R Piva
– volume: 184
  start-page: 1495
  year: 1996
  ident: BFleu2017203_CR2
  publication-title: J Exp Med
  doi: 10.1084/jem.184.4.1495
  contributor:
    fullname: H Kanzler
– volume: 25
  start-page: 2679
  year: 2006
  ident: BFleu2017203_CR49
  publication-title: Oncogene
  doi: 10.1038/sj.onc.1209151
  contributor:
    fullname: MA Weniger
– volume: 18
  start-page: 1611
  year: 2012
  ident: BFleu2017203_CR13
  publication-title: Clin Cancer Res
  doi: 10.1158/1078-0432.CCR-11-1942
  contributor:
    fullname: MR Green
– volume: 205
  start-page: 2251
  year: 2008
  ident: BFleu2017203_CR14
  publication-title: J Exp Med
  doi: 10.1084/jem.20080809
  contributor:
    fullname: V Brune
– volume: 490
  start-page: 502
  year: 2012
  ident: BFleu2017203_CR20
  publication-title: Nature
  doi: 10.1038/nature11531
  contributor:
    fullname: R Tussiwand
– volume: 490
  start-page: 543
  year: 2012
  ident: BFleu2017203_CR28
  publication-title: Nature
  doi: 10.1038/nature11530
  contributor:
    fullname: P Li
– volume: 16
  start-page: 698
  year: 2008
  ident: BFleu2017203_CR22
  publication-title: Mol Ther
  doi: 10.1038/mt.2008.6
  contributor:
    fullname: K Weber
– volume: 322
  start-page: 1097
  year: 2008
  ident: BFleu2017203_CR18
  publication-title: Science
  doi: 10.1126/science.1164206
  contributor:
    fullname: K Hildner
– volume: 23
  start-page: 2129
  year: 2009
  ident: BFleu2017203_CR5
  publication-title: Leukemia
  doi: 10.1038/leu.2009.161
  contributor:
    fullname: S Eckerle
– volume: 278
  start-page: 50024
  year: 2003
  ident: BFleu2017203_CR32
  publication-title: J Biol Chem
  doi: 10.1074/jbc.M308617200
  contributor:
    fullname: C Iavarone
– volume: 66
  start-page: 848
  year: 1985
  ident: BFleu2017203_CR7
  publication-title: Blood
  doi: 10.1182/blood.V66.4.848.848
  contributor:
    fullname: H Stein
– volume: 92
  start-page: 913
  year: 2007
  ident: BFleu2017203_CR42
  publication-title: Haematologica
  doi: 10.3324/haematol.11073
  contributor:
    fullname: T Feys
– volume: 39
  start-page: 294
  year: 2015
  ident: BFleu2017203_CR33
  publication-title: Am J Surg Pathol
  doi: 10.1097/PAS.0000000000000365
  contributor:
    fullname: KM Chisholm
– volume: 470
  start-page: 115
  year: 2011
  ident: BFleu2017203_CR52
  publication-title: Nature
  doi: 10.1038/nature09671
  contributor:
    fullname: VN Ngo
– volume: 99
  start-page: 618
  year: 2002
  ident: BFleu2017203_CR38
  publication-title: Blood
  doi: 10.1182/blood.V99.2.618
  contributor:
    fullname: BF Skinnider
– volume: 113
  start-page: E7260
  year: 2016
  ident: BFleu2017203_CR53
  publication-title: Proc Natl Acad Sci USA
  doi: 10.1073/pnas.1610970113
  contributor:
    fullname: L Rui
– volume: 120
  start-page: 3530
  year: 2012
  ident: BFleu2017203_CR24
  publication-title: Blood
  doi: 10.1182/blood-2012-06-439570
  contributor:
    fullname: C Steidl
– volume: 198
  start-page: 851
  year: 2003
  ident: BFleu2017203_CR15
  publication-title: J Exp Med
  doi: 10.1084/jem.20031074
  contributor:
    fullname: A Rosenwald
– volume: 126
  start-page: 17
  year: 2015
  ident: BFleu2017203_CR6
  publication-title: Blood
  doi: 10.1182/blood-2014-10-567461
  contributor:
    fullname: G Hapgood
– volume: 21
  start-page: 723
  year: 2012
  ident: BFleu2017203_CR57
  publication-title: Cancer Cell
  doi: 10.1016/j.ccr.2012.05.024
  contributor:
    fullname: Y Yang
– volume: 65
  start-page: 7628
  year: 2005
  ident: BFleu2017203_CR27
  publication-title: Cancer Res
  doi: 10.1158/0008-5472.CAN-05-0925
  contributor:
    fullname: M Watanabe
– volume: 101
  start-page: 4013
  year: 2003
  ident: BFleu2017203_CR25
  publication-title: Blood
  doi: 10.1182/blood-2002-08-2673
  contributor:
    fullname: GH Underhill
– volume: 140
  start-page: 516
  year: 2008
  ident: BFleu2017203_CR43
  publication-title: Br J Haematol
  doi: 10.1111/j.1365-2141.2007.06924.x
  contributor:
    fullname: I Salaverria
– volume: 111
  start-page: E4513
  year: 2014
  ident: BFleu2017203_CR54
  publication-title: Proc Natl Acad Sci USA
  doi: 10.1073/pnas.1406985111
  contributor:
    fullname: S Kreher
– volume: 18
  start-page: 1365
  year: 2005
  ident: BFleu2017203_CR10
  publication-title: Mod Pathol
  doi: 10.1038/modpathol.3800419
  contributor:
    fullname: GZ Rassidakis
– volume: 163
  start-page: 633
  year: 2003
  ident: BFleu2017203_CR26
  publication-title: Am J Pathol
  doi: 10.1016/S0002-9440(10)63690-5
  contributor:
    fullname: M Watanabe
– volume: 112
  start-page: 3339
  year: 2008
  ident: BFleu2017203_CR45
  publication-title: Blood
  doi: 10.1182/blood-2008-01-134783
  contributor:
    fullname: B Lamprecht
– volume: 14
  start-page: 3338
  year: 2008
  ident: BFleu2017203_CR12
  publication-title: Clin Cancer Res
  doi: 10.1158/1078-0432.CCR-07-4709
  contributor:
    fullname: SJ Rodig
– volume: 93
  start-page: 1318
  year: 2008
  ident: BFleu2017203_CR40
  publication-title: Haematologica
  doi: 10.3324/haematol.12875
  contributor:
    fullname: S Hartmann
– volume: 13
  start-page: 499
  year: 2013
  ident: BFleu2017203_CR19
  publication-title: Nat Rev Immunol
  doi: 10.1038/nri3470
  contributor:
    fullname: TL Murphy
– volume: 167
  start-page: 514
  year: 2014
  ident: BFleu2017203_CR39
  publication-title: Br J Haematol
  doi: 10.1111/bjh.13079
  contributor:
    fullname: V Atsaves
– volume: 55
  start-page: 278
  year: 2016
  ident: BFleu2017203_CR41
  publication-title: Genes Chromosomes Cancer
  doi: 10.1002/gcc.22331
  contributor:
    fullname: SJ Salipante
– volume: 13
  start-page: 1029
  year: 2012
  ident: BFleu2017203_CR58
  publication-title: Nat Immunol
  doi: 10.1038/ni.2455
  contributor:
    fullname: AL Shaffer
SSID ssj0014766
Score 2.4816236
Snippet Classical Hodgkin lymphoma (cHL) and anaplastic large cell lymphoma (ALCL) feature high expression of activator protein-1 (AP-1) transcription factors, which...
SourceID proquest
gale
crossref
pubmed
springer
SourceType Aggregation Database
Index Database
Publisher
StartPage 92
SubjectTerms 13
13/31
13/44
13/51
13/89
13/95
631/45/612/822
631/67/1990/291/1556
631/67/1990/291/1621
631/67/395
631/80/86
82
Activator protein 1
Anaplastic large-cell lymphoma
B-cell lymphoma
Basic-Leucine Zipper Transcription Factors - genetics
Cancer Research
Carcinogenesis - genetics
Carcinogenesis - pathology
Care and treatment
CD30 antigen
Cell Line, Tumor
Cell Proliferation - genetics
Cell Survival
Chromatin
Critical Care Medicine
Development and progression
Gene expression
Gene Expression Regulation, Neoplastic - genetics
Genetic aspects
Health aspects
Hematology
Hodgkin Disease - genetics
Hodgkin Disease - pathology
Hodgkin's lymphoma
Humans
Immunoprecipitation
Intensive
Interleukin 13
Internal Medicine
Janus kinase 2
Janus Kinase 2 - genetics
JunB protein
Leucine
Leucine zipper proteins
Lymphocytes B
Lymphoma
Lymphoma, Large B-Cell, Diffuse - genetics
Lymphoma, Large B-Cell, Diffuse - pathology
Lymphoma, Large-Cell, Anaplastic - genetics
Lymphoma, Large-Cell, Anaplastic - pathology
Lymphomas
Mass spectrometry
Mass spectroscopy
Medicine
Medicine & Public Health
Myc protein
Oncogenes - genetics
Oncology
original-article
Physiological effects
Promoter Regions, Genetic - genetics
Proteins
Proto-Oncogene Proteins c-myc - genetics
RNA, Small Interfering - genetics
Signal Transduction - genetics
Signaling
STAT Transcription Factors - genetics
Survival
Transcription Factor AP-1 - genetics
Transcription factors
Transcriptional Activation - genetics
Up-Regulation - genetics
Title An oncogenic axis of STAT-mediated BATF3 upregulation causing MYC activity in classical Hodgkin lymphoma and anaplastic large cell lymphoma
URI https://link.springer.com/article/10.1038/leu.2017.203
https://www.ncbi.nlm.nih.gov/pubmed/28659618
https://www.proquest.com/docview/1986186071
https://search.proquest.com/docview/1914846212
Volume 32
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1La9tAEB4aG3or6Vtp6myhj5OIrX1IOhXZxJiCTWkdcE9itVoFU1dy_YD2N_RPd0ZaK3EoPXgP0sisNDs73-y8AN6qDEG-LrjPrQh8EWnjZzREMstRP8WSG8odns7U5Fp8WsiFO3DburDKw55Yb9R5ZeiM_BKNYyrtjhrx4_qnT12jyLvqWmicQDdASyHoQHd4Nfv8pfUjiLDxVpIoKTQ1XOh7n0eXK7unyK4QB36klO5vzXd00z1naa2DxqfwyIFHljTcfgwPbPkEHk6de_wp_ElKVpWmwkWxNEz_Wm5ZVbCv82Tu1xkiiC7ZMJmPOduvN00TemQLM5qi32_Y9NuIUZ4DtZNgS7xOyJqYyCZVfvMdr6x-I_OrH5rpMsefXiMFzoWtKJ6ckROgJXkG1-Or-Wjiu24LvhFS7nyRDeJCFkFfhHnAuQilUXmco7mEIFCZyPK8UFGsYxHZQgYyQ0Ml0yYvRGjQyrX8OXTKqrQvgWVoQ1lVIPKKlTBUA05nYaQV1RsrbN968O7wudN1U1QjrZ3hPEqRLSmxBQfuwQXxIm1SQltZTBMEjQO03aXw4ENNQdK422ijXVIBzoPqWh1Rnh9RohSZ49sHfqdOirfp7Zrz4E17m56kyLTSVnuiwS8kFCIAD14066R9J8r6pY46Hrw_LJw7f_6PFz77_yxe0akCdeOgE6Bz6Ow2e_saMdEu68FJuAhxjEaDHnST8XA46zlh-AuodwxD
link.rule.ids 315,783,787,12070,12237,21402,27938,27939,31733,31734,33280,33281,33758,33759,43324,43593,43819,74081,74350,74638
linkProvider ProQuest
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfR3LjtMwcASLBFwQbwILayQep2jb-hHnhMKKqsB2L2Slcoocx15VlKT0IcE38NPMJG7YrhCH-OCMIzvj8cx4XgCvVIlCvvE85k6MYqGNjUtqtCwr5E-p5JZih6dnanIuPs3kLFy4rYNb5e5MbA_qqrF0R36MyjGldkeO-G75I6aqUWRdDSU0rsMNysNFufOTWa9wDUXS2SqJkBQqGsHxfcD18cJtya8rwYbvsaSrB_MlznTFVNpyoPFduBNER5Z1uL4H11x9H25Og3H8AfzOatbUtsEtMbfM_JyvWePZlzzL4zY-BGVL9j7Lx5xtl6uuBD0ihVlDvu8XbPr1hFGUAxWTYHPsJ7maUMgmTXXxDXsWvxD1zXfDTF3hY5YIgXNhC_ImZ2QC6EEewvn4Q34yiUOthdgKKTexKIepl340EEk14lwk0qoqrVBZQhFQWe145ZVOTSq083IkS1RTSmMrLxKLOq7jj-Cgbmr3BFiJGpRTHuWuVAlLGeBMmWijKNuYdwMXwevd7y6WXUqNojWFc10gWgpCCzY8giPCRdEFhPaUWGQoMg5Rc5cigrctBNHiZmWsCSEFOA_KarUHebgHiTRk91_v8F0EGl4Xf3dcBC_71zSS_NJq12wJBv-QUMj_I3jc7ZN-TRTzS_V0Iniz2ziXPv6PBT_9_yyO4NYkn54Wpx_PPj-D2zhKd3dBh3CwWW3dc5SONuWLlgT-AAHUCqU
linkToPdf http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1Lb9NAEB5BkSouiPKqoaWLxONkJfE-bJ8qE4jCIxUSqVRO1nq9W0UEO-QhwW_gT3fG3pimQhy8B3tsrT0zO994ZnYAXqoCQb52PORWRKFItAkLGhJZlGifUskN1Q5PztT4XHy8kBc-_2nl0yq3a2KzUJe1oX_kPXSOaWt3tIg959MivrwbnS5-htRBiiKtvp3GbbiDVlFSG4dk2KV7DETcxi1JqRQ6HT4Jvs-T3txuKMcrxoHvmKebi_Q1K3UjbNpYo9F9uOdhJMtavh_ALVs9gP2JD5Q_hD9ZxerK1CgeM8P0r9mK1Y59nWbTsKkVQZzJ3mbTEWebxbJtR48MYkZTHvwlm3wbMqp4oMYSbIbnCWMTO9m4Li-_45n5bxSD-odmuirx0AukwLmwOWWWMwoHdCSP4Hz0fjoch77vQmiElOtQFIPUSRf1RVxGnItYGlWmJTpOCAeVSSwvnUpSnYrEOhnJAl2WQpvSidigv2v5Y9ir6soeAivQm7LKIQZLlTC0G5wu4kQr2nnM2b4N4NX2c-eLdnuNvAmL8yRHtuTEFhx4ACfEi7wtDu20Ms8QPg7Qi5cigDcNBenleqmN9uUFOA_a4WqH8miHEvXJ7F7e8jv3-rzK_0pfAC-6y3Qn5ahVtt4QDX4hoRALBPCklZPunaj-l3rrBPB6KzjXHv6PF376_1mcwD5Kf_75w9mnZ3A3QuBF_5sH_Aj21suNPUagtC6eNxpwBV5uDqo
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=An+oncogenic+axis+of+STAT-mediated+BATF3+upregulation+causing+MYC+activity+in+classical+Hodgkin+lymphoma+and+anaplastic+large+cell+lymphoma&rft.jtitle=Leukemia&rft.au=Lollies%2C+A&rft.au=Hartmann%2C+S&rft.au=Schneider%2C+M&rft.au=Bracht%2C+T&rft.date=2018-01-01&rft.eissn=1476-5551&rft.volume=32&rft.issue=1&rft.spage=92&rft_id=info:doi/10.1038%2Fleu.2017.203&rft_id=info%3Apmid%2F28659618&rft.externalDocID=28659618
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0887-6924&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0887-6924&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0887-6924&client=summon