The Chemical Biology of Human Metallo-β-Lactamase Fold Proteins

The αββα metallo β-lactamase (MBL) fold (MBLf) was first observed in bacterial enzymes that catalyze the hydrolysis of almost all β-lactam antibiotics, but is now known to be widely distributed. The MBL core protein fold is present in human enzymes with diverse biological roles, including cell detox...

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Published inTrends in biochemical sciences (Amsterdam. Regular ed.) Vol. 41; no. 4; pp. 338 - 355
Main Authors Pettinati, Ilaria, Brem, Jürgen, Lee, Sook Y., McHugh, Peter J., Schofield, Christopher J.
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 01.04.2016
Elsevier Trends Journals
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