Requirement for memory B-cell activation in protection from heterologous influenza virus reinfection

• Published in: International immunology Vol. 31; no. 12; pp. 771 - 779
• Main Authors: Leach, Sarah, Shinnakasu, Ryo, Adachi, Yu, Momota, Masatoshi, Makino-Okamura, Chieko, Yamamoto, Takuya, Ishii, Ken J, Fukuyama, Hidehiro, Takahashi, Yoshimasa, Kurosaki, Tomohiro
• Format: Journal Article
• Language: English
• Published: UK Oxford University Press 08.11.2019
• Subjects: Animals; B-Lymphocytes - immunology; B-Lymphocytes - metabolism; Immunologic Memory - immunology; Lymphocyte Activation - immunology; Macrophages - immunology; Macrophages - metabolism; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Orthomyxoviridae - immunology; Orthomyxoviridae - physiology; infection; antibody; immunity; virus; cross-reactive

Memory B cells protect against heterologous influenza infection Abstract While two memory compartments, memory B cells and long-lived plasma cells, are thought to contribute to the successful establishment of memory recall responses, the unique roles of each cellular compartment are still unclear. H...