NIR-II/NIR-I Fluorescence Molecular Tomography of Heterogeneous Mice Based on Gaussian Weighted Neighborhood Fused Lasso Method

• Published in: IEEE transactions on medical imaging Vol. 39; no. 6; pp. 2213 - 2222
• Main Authors: Cai, Meishan, Zhang, Zeyu, Shi, Xiaojing, Hu, Zhenhua, Tian, Jie
• Format: Journal Article
• Language: English
• Published: United States IEEE 01.06.2020; The Institute of Electrical and Electronics Engineers, Inc. (IEEE)
• Subjects: Accuracy; Algorithms; Biomarkers; Biomedical materials; Biomedical optical imaging; Computer simulation; Fluorescence; Fluorescence molecular tomography; GWNFL method; I.R. radiation; Image reconstruction; Imaging techniques; In vivo; In vivo methods and tests; Infrared windows; Inverse problems; Light scattering; Lymph nodes; Mathematical models; Molecular imaging; Near infrared radiation; NIR-I; NIR-II; Optical properties; Optical scattering; Reconstruction; Tomography

Fluorescence molecular tomography (FMT), which can visualize the distribution of fluorescence biomarkers, has become a novel three-dimensional noninvasive imaging technique for in vivo studies such as tumor detection and lymph node location. However, it remains a challenging problem to achieve satis...