The isolation, total synthesis and structure elucidation of chlorofusin, a natural product inhibitor of the p53–MDM2 protein–protein interaction - Clark, Ryan C.; Lee, Sang Yeul; Searcey, Mark; Boger, Dale L. (Natural product reports, 2009)
Keywords: Antineoplastic Agents - chemical synthesis; Antineoplastic Agents - chemistry; Antineoplastic Agents - isolation & purification; Antineoplastic Agents - pharmacology; biological assessment; Drug Design; Fusarium - chemistry; Molecular Structure; neoplasms; Neoplasms - drug therapy; Peptides, Cyclic - chemical synthesis; Peptides, Cyclic - chemistry; Peptides, Cyclic - isolation & purification; Peptides, Cyclic - pharmacology; protein-protein interactions; Proto-Oncogene Proteins c-mdm2 - antagonists & inhibitors; Proto-Oncogene Proteins c-mdm2 - metabolism; stereochemistry; therapeutics; Tumor Suppressor Protein p53 - antagonists & inhibitors; Tumor Suppressor Protein p53 - metabolism