Diabetes, obesity, metabolism, and SARS-CoV-2 infection: the end of the beginning

• Published in: Cell metabolism Vol. 33; no. 3; pp. 479 - 498
• Main Author: Drucker, Daniel J.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 02.03.2021
• Subjects: adipose tissue; Angiotensin-Converting Enzyme 2 - metabolism; Blood Glucose - analysis; Cholesterol - metabolism; Comorbidity; COVID-19 - epidemiology; COVID-19 - pathology; COVID-19 Drug Treatment; Diabetes Mellitus - pathology; Genetic Predisposition to Disease - genetics; glucose; Glucose - metabolism; Heart Disease Risk Factors; Humans; Hyperglycemia - pathology; immunity; islet; Metabolic Diseases - pathology; Obesity - pathology; Review; SARS-CoV-2; vaccination; virus; adipose tissue; glucose; immunity; islet; virus; vaccination

The increased prevalence of obesity, diabetes, and cardiovascular risk factors in people hospitalized with severe COVID-19 illness has engendered considerable interest in the metabolic aspects of SARS-CoV-2-induced pathophysiology. Here, I update concepts informing how metabolic disorders and their...