A Single-Cell Transcriptome Atlas of the Human Pancreas

• Published in: Cell systems Vol. 3; no. 4; pp. 385 - 394.e3
• Main Authors: Muraro, Mauro J., Dharmadhikari, Gitanjali, Grün, Dominic, Groen, Nathalie, Dielen, Tim, Jansen, Erik, van Gurp, Leon, Engelse, Marten A., Carlotti, Francoise, de Koning, Eelco J.P., van Oudenaarden, Alexander
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 26.10.2016; Cell Press
• Subjects: Acinar Cells; Diabetes Mellitus, Type 1; Humans; Insulin; islets of Langerhans; Membrane Glycoproteins; Pancreas; sequencing; Single-Cell Analysis; single-cell transcriptomics; Transcriptome; single-cell transcriptomics; pancreas; islets of Langerhans; sequencing

To understand organ function, it is important to have an inventory of its cell types and of their corresponding marker genes. This is a particularly challenging task for human tissues like the pancreas, because reliable markers are limited. Hence, transcriptome-wide studies are typically done on poo...