pharmacokinetics and pharmacodynamics of prasugrel in healthy Chinese, Japanese, and Korean subjects compared with healthy Caucasian subjects - Small, David S; Kothare, Prajakti; Yuen, Eunice; Lachno, D. Richard; Li, Ying G; Winters, Kenneth J; Farid, Nagy A; Ni, Lan; Jakubowski, Joseph A; Salazar, Daniel E; Thieu, Vivian T; Payne, Christopher D (European journal of clinical pharmacology, 2010)
Keywords: Acute coronary syndromes; Adenosine Diphosphate - pharmacology; Adult; Aged; Asian Continental Ancestry Group; Asian people; Biological and medical sciences; Biomedical and Life Sciences; Biomedicine; Body Mass Index; Clinical Trial; Clinical trials; Dose-Response Relationship, Drug; European Continental Ancestry Group; Female; Humans; Inhibitor drugs; Male; Medical sciences; Middle Aged; Pharmacology; Pharmacology. Drug treatments; Pharmacology/Toxicology; Piperazines - administration & dosage; Piperazines - adverse effects; Piperazines - blood; Piperazines - pharmacokinetics; Piperazines - pharmacology; Platelet Aggregation - drug effects; Platelet Aggregation Inhibitors - administration & dosage; Platelet Aggregation Inhibitors - adverse effects; Platelet Aggregation Inhibitors - pharmacokinetics; Platelet Aggregation Inhibitors - pharmacology; Prasugrel Hydrochloride; Prodrugs - administration & dosage; Prodrugs - adverse effects; Prodrugs - pharmacokinetics; Prodrugs - pharmacology; Statistics as Topic; Thiophenes - administration & dosage; Thiophenes - adverse effects; Thiophenes - pharmacokinetics; Thiophenes - pharmacology; White people; Young Adult; Asia; China; Japan; Korea; Prasugrel; Pharmacodynamics; Inhibition of platelet aggregation; Pharmacokinetics; Asians; Human; Pharmacokinetic pharmacodynamic relationship; Asiatic; Healthy subject; Ethnic group; Biological activity; Antiplatelet agent; Aggregation; Platelet; Hemostasis; Platelet function; Antithrombotic agent; Chinese; Caucasoid; Comparative study