Topical transfection using plasmid DNA in a water-in-oil nanoemulsion - Wu, Huailiang; Ramachandran, Chandrasekharan; Bielinska, Anna U; Kingzett, Kristen; Sun, Rong; Weiner, Norman D; Roessler, Blake J (International journal of pharmaceutics, 2001)
Keywords: Administration, Topical; Animals; Biological and medical sciences; Chemistry, Pharmaceutical; Chloramphenicol O-Acetyltransferase - administration & dosage; DNA Transposable Elements - genetics; DNA, Complementary - genetics; Emulsions; Enzyme-Linked Immunosorbent Assay; General pharmacology; In vivo transfection; Keratinocytes; Male; Medical sciences; Mice; Mice, Hairless; Mice, Inbred C57BL; Non-viral vectors; Pharmaceutical technology. Pharmaceutical industry; Pharmacology. Drug treatments; Plasmids - genetics; Reverse Transcriptase Polymerase Chain Reaction; Skin - pathology; Skin Absorption; Transfection; Transgenes - genetics; Water-in-oil nanoemulsions; Water-in-oil nanoemulsions; Keratinocytes; Non-viral vectors; In vivo transfection; Water oil emulsion; Pharmaceutical technology; Toxicity; Rodentia; Liposome; Drug carrier; Gene expression; Percutaneous route; Plasmid; Vertebrata; Mammalia; Transfection; Mouse; Animal; DNA; Dosage form; Skin; Gene therapy; Comparative study