The Golgi apparatus and the centrosome are localized to the sites of newly emerging axons in cerebellar granule neurons in vitro

• Published in: Cell motility and the cytoskeleton Vol. 41; no. 1; p. 18
• Main Authors: Zmuda, J F, Rivas, R J
• Format: Journal Article
• Language: English
• Published: United States 1998
• Subjects: Animals; Axons; Cell Differentiation; Cell Polarity; Cells, Cultured; Centrosome; Cerebellar Cortex - cytology; Culture Media, Serum-Free; Dendrites; Golgi Apparatus; Mice; Mice, Inbred C57BL; Microtubule-Associated Proteins - analysis; Neurons - cytology; tau Proteins - analysis

Cultured cerebellar granule neurons develop their characteristic axonal and dendritic morphologies in a series of discrete temporal steps highly similar to those observed in situ, initially extending a single process, followed by the extension of a second process from the opposite pole of the cell,...