Safety, efficacy and anti-inflammatory activity of rho iso-alpha-acids from hops - Hall, Amy J.; Babish, John G.; Darland, Gary K.; Carroll, Brian J.; Konda, Veera Reedy; Lerman, Robert H.; Bland, Jeffery S.; Tripp, Matthew L. (Phytochemistry (Oxford), 2008)
Keywords: Adult; adverse effects; Aged; Alkanes; Alkanes - adverse effects; Alkanes - pharmacokinetics; Alkanes - therapeutic use; Animals; Anti-inflammatory; anti-inflammatory activity; Anti-Inflammatory Agents; Anti-Inflammatory Agents - adverse effects; Anti-Inflammatory Agents - pharmacokinetics; Anti-Inflammatory Agents - therapeutic use; Biological and medical sciences; Biological Availability; blood chemistry; blood pressure; Body Weight; Body Weight - drug effects; Calprotectin; Cannabidaceae; Cell Line; Chemical constitution; chemistry; Chromatography, Liquid; cultured cells; Cyclooxygenase; Cyclooxygenase Inhibitors; Cyclooxygenase Inhibitors - adverse effects; Cyclooxygenase Inhibitors - pharmacokinetics; Cyclooxygenase Inhibitors - therapeutic use; Cyclopentanes; Cyclopentanes - adverse effects; Cyclopentanes - pharmacokinetics; Cyclopentanes - therapeutic use; drug effects; enzyme activity; Feces; Feces - chemistry; Female; Fundamental and applied biological sciences. Psychology; General pharmacology; Hops; Humans; Humulus; Humulus - chemistry; Humulus lupulus; Humulus lupulus L; Kidney; Kidney - drug effects; Kidney - pathology; Knee osteoarthritis; Leukocyte L1 Antigen Complex; Leukocyte L1 Antigen Complex - metabolism; Liver; Liver - drug effects; Liver - pathology; Male; Mass Spectrometry; Medical sciences; metabolism; Mice; Middle Aged; NSAID; Organ Size; Organ Size - drug effects; osteoarthritis; Osteoarthritis - pathology; Osteoarthritis - prevention & control; pathology; PGE 2; Pharmacognosy. Homeopathy. Health food; pharmacokinetics; Pharmacology. Drug treatments; phytochemicals; Plant Extracts; Plant Extracts - adverse effects; Plant Extracts - pharmacokinetics; Plant Extracts - therapeutic use; Plant physiology and development; prevention & control; Prostaglandin; prostaglandin synthase; prostaglandins; Prostaglandins - urine; Rho iso-alpha-acids; therapeutic use; Treatment Outcome; urine; Cyclooxygenase; Humulus lupulus L; Knee osteoarthritis; Prostaglandin; Rho iso-alpha-acids; NSAID; Hops; PGE 2; Cannabidaceae; Calprotectin