Anti-Inflammatory Activity of Chitosan and 5-Amino Salicylic Acid Combinations in Experimental Colitis

• Published in: Pharmaceutics Vol. 12; no. 11; p. 1038
• Main Authors: Jhundoo, Henusha D., Siefen, Tobias, Liang, Alfred, Schmidt, Christoph, Lokhnauth, John, Béduneau, Arnaud, Pellequer, Yann, Larsen, Crilles Casper, Lamprecht, Alf
• Format: Journal Article
• Language: English
• Published: MDPI 29.10.2020; MDPI AG
• Subjects: 5-amino salicylic acid; chitosan; colitis; IBD; inflammation; RAW 264.7 macrophages

Chitosan is used in various drug delivery approaches as a pharmaceutical excipient. Although its potential as an immunomodulatory agent has been reported, its use in this capacity has not been fully explored. The efficacy of chitosan as an active pharmacological agent, particularly in anti-inflammat...