Plasma Cell-Free DNA and Caspase-3 Levels in Patients with Chronic Kidney Disease

• Published in: Journal of clinical medicine Vol. 12; no. 17; p. 5616
• Main Authors: Clementi, Anna, Virzì, Grazia Maria, Manani, Sabrina Milan, de Cal, Massimo, Battaglia, Giovanni Giorgio, Ronco, Claudio, Zanella, Monica
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 28.08.2023; MDPI
• Subjects: Apoptosis; Care and treatment; Chronic kidney failure; Clinical medicine; Creatinine; Development and progression; DNA; Enzymes; Ethylenediaminetetraacetic acid; Extrachromosomal DNA; Health aspects; Heart attack; Hemodialysis; Inflammation; Japan; Kidney diseases; Measurement; Medical research; Medicine, Experimental; Mitochondrial DNA; Mortality; Peritoneal dialysis; Pilot projects; Plasma; Rankings; Statistical analysis; Italy; Japan; United States > US

Background: Cell-free plasma DNA (cfDNA) is circulating extracellular DNA arising from cell death mechanisms (apoptosis, necrosis, etc.). It is commonly existent in healthy individuals, but its ranks increase in diverse clinical circumstances, such as kidney disease, sepsis, myocardial infarction, t...