Antibodies to HIV integrase catalyze site-specific degradation of their antigen - Odintsova, Elena S.; Baranova, Svetlana V.; Dmitrenok, Pavel S.; Rasskazov, Valeriy A.; Calmels, Christina; Parissi, Vincent; Andreola, Marie-Line; Buneva, Valentina N.; Zakharova, Olga D.; Nevinsky, Georgy A. (International immunology, 2011)
Keywords: Acquired immune deficiency syndrome; Adolescent; Adult; Affinity chromatography; Antibodies; Biocatalysis; Chymotrypsin; DNA; Endopeptidase K; Female; Genomes; HIV Antibodies; HIV Antibodies - blood; HIV Antibodies - immunology; HIV Antigens; HIV Antigens - immunology; HIV Antigens - metabolism; HIV Infections; HIV Infections - blood; HIV Infections - immunology; HIV Integrase; HIV Integrase - immunology; HIV Integrase - metabolism; Human immunodeficiency virus 1; Humans; Immunoglobulin G; Immunoglobulin G - blood; Immunoglobulin G - immunology; Immunoglobulin M; Immunoglobulin M - blood; Immunoglobulin M - immunology; Infection; Integrase; Integration; Life Sciences; Male; Mass spectroscopy; Microbiology and Parasitology; Oligopeptides; Proteinase; Substrate Specificity; Trypsin; Young Adult; HIV- infected patients; human blood antibodies; catalytic antibodies; hydrolysis of HIV integrase