Iodinated Copper–Cysteamine Nanoparticles as Radiosensitizers for Tumor Radiotherapy

• Published in: Pharmaceutics Vol. 17; no. 2; p. 149
• Main Authors: Zhang, Miaomiao, Yang, Yu, Xu, Ying, Wang, Jie, Li, Shihong
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 22.01.2025; MDPI
• Subjects: 131I; Biotechnology; Cancer therapies; Copper; copper–cysteamine nanoparticles; Light; Nanoparticles; Ovarian cancer; Photodynamic therapy; Polyvinyl alcohol; Radiation therapy; Radioactivity; radiosensitization; radiotherapy; Reactive oxygen species; Tumors; X-ray-induced photodynamic therapy; radiotherapy; X-ray-induced photodynamic therapy; copper–cysteamine nanoparticles; 131I; radiosensitization

Background/Objectives: Radiotherapy is a widely applied first-line clinical treatment modality of cancer. Copper–cysteamine (Cu-Cy) nanoparticles represent a new type of photosensitizer that demonstrates significant anti-tumor potential by X-ray-induced photodynamic therapy. Iodide is a high-Z eleme...