Host–Biofilm Interactions

• Published in: Microorganisms (Basel) Vol. 10; no. 8; p. 1641
• Main Authors: Chen, Yun, Kolodkin-Gal, Ilana
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 13.08.2022; MDPI
• Subjects: Anaerobic conditions; Antibiotics; Antiinfectives and antibacterials; Antimicrobial agents; Bacteria; Biofilms; Cell division; Community; Conflicts of interest; Crosstalk; Dental caries; Dermatology; Extracellular matrix; Homeostasis; Hormones; Host-bacteria relationships; Microbial mats; Microbiological research; Microbiota; Microenvironments; n/a; Pathogens; Peptides; Physiological aspects; Plant roots; Polystyrene; Polystyrene resins; Stainless steel; Stainless steels; Staphylococcus infections; Urogenital system; China
• ISSN: 2076-2607; 2076-2607
• DOI: 10.3390/microorganisms10081641

An additional example is beneficial biofilms associated with the plant root, such as Bacillus subtilis and its clade members [4,5] where the adherent bacteria protect their hosts from fungal, bacterial, and viral pathogens [6,7]. Biofilms associated with the skin reside in a complex microenvironment subject to host-derived peptide signaling. [...]studying the biofilm–host crosstalk may expose novel approaches for antimicrobial therapies in cosmetology and dermatology. The authors expose the potential roles of NE in multispecies skin-associated communities and suggest that NE has a primary role as a regulator of biofilm growth and maturation and that biofilms of both species are more sensitive to NE in anaerobic conditions. Condition-dependent biofilm regulation was identified by (p)ppGpp synthase SpoT as spoT mutants all presented an increased ability to produce biofilms on polystyrene and stainless steel but had reduced biofilm-forming capacity on glass.