Magnetic Resonance Imaging Analysis of Right Ventricular Pressure-Volume Loops In Vivo Validation and Clinical Application in Patients With Pulmonary Hypertension

• Published in: Circulation (New York, N.Y.) Vol. 110; no. 14; pp. 2010 - 2016
• Main Authors: Kuehne, Titus, Yilmaz, Sevim, Steendijk, Paul, Moore, Phillip, Groenink, Maarten, Saaed, Maythem, Weber, Oliver, Higgins, Charles B., Ewert, Peter, Fleck, Eckard, Nagel, Eike, Schulze-Neick, Ingram, Lange, Peter
• Format: Journal Article
• Language: English
• Published: Hagerstown, MD Lippincott Williams & Wilkins 05.10.2004
• Subjects: Adolescent; Adult; Animals; Biological and medical sciences; Blood and lymphatic vessels; Cardiac Catheterization; Cardiology. Vascular system; Cardiomegaly - etiology; Cardiomegaly - pathology; Cardiovascular system; Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous; Embolism, Paradoxical - etiology; Female; Heart Septal Defects, Atrial - complications; Heart Septal Defects, Atrial - pathology; Humans; Hypertension, Pulmonary - complications; Hypertension, Pulmonary - pathology; Hypertension, Pulmonary - physiopathology; Magnetic Resonance Imaging, Cine; Male; Medical sciences; Middle Aged; Myocardial Contraction; Myocardium - pathology; Organ Size; Pharmacology. Drug treatments; Pneumology; Pressure; Pulmonary hypertension. Acute cor pulmonale. Pulmonary embolism. Pulmonary vascular diseases; Pulmonary Wedge Pressure; Sus scrofa; Vascular Resistance; Vasodilator agents. Cerebral vasodilators; Ventricular Dysfunction, Right - etiology; Ventricular Dysfunction, Right - pathology; Ventricular Dysfunction, Right - physiopathology; Ventricular Function, Right; Human; magnetic resonance imaging; myocardial contraction; Respiratory disease; hypertension, pulmonary; Cardiovascular disease; heart defects, congenital; Nuclear magnetic resonance imaging; Pulmonary hypertension; ventricles

Background— The aims of this study were to validate MRI-derived right ventricular (RV) pressure-volume loops for assessment of RV myocardial contractility and then to apply this technique in patients with chronic RV pressure overload for assessment of myocardial contractility, ventricular pump funct...