Kidney glycosphingolipids are elevated early in diabetic nephropathy and mediate hypertrophy of mesangial cells - Subathra, Marimuthu; Korrapati, Midhun; Howell, Lauren A.; Arthur, John M.; Shayman, James A.; Schnellmann, Rick G.; Siskind, Leah J. (American journal of physiology. Renal physiology, 2015)
Keywords: Animals; Antigens, CD - metabolism; Cell Line; Cell Proliferation; Diabetes; Diabetes Mellitus, Experimental - pathology; Diabetic Nephropathies - metabolism; Diabetic Nephropathies - pathology; Glycosphingolipids - metabolism; Humans; Kidney - metabolism; Kidney diseases; Kidney Glomerulus - pathology; Kidney Tubules, Proximal - pathology; Lactosylceramides - metabolism; Lipids; Matrix; Mesangial Cells - pathology; Mesangial Cells - ultrastructure; Mice; Oncogene Protein v-akt - metabolism; Proteins; Rodents; Signal Transduction; Smad3 Protein - metabolism; kidney; hypertrophy; mesangial cells; diabetic nephropathy; glycosphingolipids