Cobalt Oxide Nanoparticles: Behavior towards Intact and Impaired Human Skin and Keratinocytes Toxicity

• Published in: International journal of environmental research and public health Vol. 12; no. 7; pp. 8263 - 8280
• Main Authors: Mauro, Marcella, Crosera, Matteo, Pelin, Marco, Florio, Chiara, Bellomo, Francesca, Adami, Gianpiero, Apostoli, Piero, De Palma, Giuseppe, Bovenzi, Massimo, Campanini, Marco, Filon, Francesca
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 17.07.2015; MDPI
• Subjects: Cell Survival - drug effects; Cobalt; Cobalt - toxicity; Diffusion; DNA Damage; Human subjects; Humans; Keratinocytes - drug effects; Keratinocytes - pathology; Nanoparticles; Nanoparticles - toxicity; Oxides - toxicity; Skin - drug effects; Skin - pathology; Skin Absorption; Toxicity; human skin absorption; nanoparticles; cobalt oxide; in vitro; keratinocytes toxicity

Skin absorption and toxicity on keratinocytes of cobalt oxide nanoparticles (Co3O4NPs) have been investigated. Co3O4NPs are commonly used in industrial products and biomedicine. There is evidence that these nanoparticles can cause membrane damage and genotoxicity in vitro, but no data are available...