Neuropsychiatric Evaluation in Subjects Chronically Exposed to Organophosphate Pesticides

• Published in: Toxicological sciences Vol. 72; no. 2; pp. 267 - 271
• Main Authors: Salvi, Rosane Maria, Lara, Diogo R., Ghisolfi, Eduardo S., Portela, Luis V., Dias, Renato D., Souza, Diogo O.
• Format: Journal Article
• Language: English
• Published: Cary, NC Oxford University Press 01.04.2003
• Subjects: acetylcholinesterase; Acetylcholinesterase - blood; Adult; Agricultural Workers' Diseases - blood; Agricultural Workers' Diseases - epidemiology; Agricultural Workers' Diseases - etiology; Biological and medical sciences; Brazil - epidemiology; Cognition Disorders - blood; Cognition Disorders - epidemiology; Cognition Disorders - etiology; Epidemiologic Studies; Female; Humans; Insecticides - adverse effects; Male; Medical sciences; Occupational Exposure; organophosphate pesticides; Organophosphorus Compounds; parkinsonism; Pesticides, fertilizers and other agrochemicals toxicology; psychiatry; Psychomotor Disorders - blood; Psychomotor Disorders - epidemiology; Psychomotor Disorders - etiology; Toxicology; South America; Brazil; America; Nervous system diseases; parkinsonism; Enzyme; Toxicity; organophosphate pesticides; Pesticides; Parkinson disease; Esterases; psychiatry; Acetylcholinesterase; Occupational exposure; Carboxylic ester hydrolases; Cerebral disorder; Chronic; Enzymatic activity; Central nervous system disease; Mental disorder; Hydrolases; Agriculture; Degenerative disease; Organophosphorus compounds; Occupational medicine

Long-term exposure to low levels of organophosphate pesticides (OP) may produce neuropsychiatric symptoms. We performed clinical, neuropsychiatric, and laboratory evaluations of 37 workers involved in family agriculture of tobacco from southern Brazil who had been exposed to OP for 3 months, and in...