Whole-Genome Characterization of Epidemic Neisseria meningitidis Serogroup C and Resurgence of Serogroup W, Niger, 2015

• Published in: Emerging infectious diseases Vol. 22; no. 10; pp. 1762 - 1768
• Main Authors: Kretz, Cecilia B., Retchless, Adam C., Sidikou, Fati, Issaka, Bassira, Ousmane, Sani, Schwartz, Stephanie, Tate, Ashley H., Pana, Assimawè, Njanpop-Lafourcade, Berthe-Marie, Nzeyimana, Innocent, Nse, Ricardo Obama, Deghmane, Ala-Eddine, Hong, Eva, Brynildsrud, Ola Brønstad, Novak, Ryan T., Meyer, Sarah A., Oukem-Boyer, Odile Ouwe Missi, Ronveaux, Olivier, Caugant, Dominique A., Taha, Muhamed-Kheir, Wang, Xin
• Format: Journal Article
• Language: English
• Published: United States Centers for Disease Control and Prevention 01.10.2016
• Subjects: Antigens, Bacterial - genetics; bacteria; Bacteriology; Communicable Diseases, Emerging; DNA, Bacterial; Drug Resistance, Bacterial - genetics; Epidemics; Genetic Variation; Genetics; Genome, Bacterial; Human health and pathology; Humans; Infectious diseases; Life Sciences; meningitis belt; Meningitis, Meningococcal - epidemiology; Meningitis, Meningococcal - microbiology; Meningococcal meningitis; Microbiology and Parasitology; Molecular Typing; Neisseria meningitidis - genetics; Neisseria meningitidis - isolation & purification; Neisseria meningitidis serogroup C; Neisseria meningitidis, Serogroup C - genetics; Neisseria meningitidis, Serogroup C - isolation & purification; Niger; Niger - epidemiology; Phylogeny; Santé publique et épidémiologie; Sequence Analysis, DNA; Serogroup C and Resurging Serogroup W, Niger, 2015; Serotyping; Whole-Genome Characterization of Epidemic; whole-genome sequencing; Neisseria meningitidis serogroup C; bacteria; meningitis belt; Niger; whole-genome sequencing; Meningococcal meningitis

In 2015, Niger reported the largest epidemic of Neisseria meningitidis serogroup C (NmC) meningitis in sub-Saharan Africa. The NmC epidemic coincided with serogroup W (NmW) cases during the epidemic season, resulting in a total of 9,367 meningococcal cases through June 2015. To clarify the phylogene...