Impact of body composition on pharmacokinetics of doxorubicin in children: a Glaser Pediatric Research Network study - Thompson, Patrick A; Rosner, Gary L; Matthay, Katherine K; Moore, Theodore B; Bomgaars, Lisa R; Ellis, Kenneth J; Renbarger, Jamie; Berg, Stacey L (Cancer chemotherapy and pharmacology, 2009)
Keywords: Adolescent; Adult; Antineoplastic agents; Antineoplastic Agents - blood; Antineoplastic Agents - pharmacokinetics; Biological and medical sciences; Body Composition; Cancer Research; Child; Child, Preschool; Doxorubicin - analogs & derivatives; Doxorubicin - blood; Doxorubicin - pharmacokinetics; Female; Humans; Infant; Male; Medical sciences; Medicine; Medicine & Public Health; Metabolic Clearance Rate; Metabolic diseases; Neoplasm Staging; Neoplasms - blood; Neoplasms - diagnosis; Obesity; Obesity - blood; Oncology; Original Article; Pharmacology. Drug treatments; Pharmacology/Toxicology; Prognosis; Prospective Studies; Treatment Outcome; Young Adult; Pediatrics; Obesity; Pharmacokinetics; Doxorubicin; Doxorubicinol; Body composition; Human; Antineoplastic agent; DNA topoisomerase (ATP-hydrolysing); Enzyme; Nutrition disorder; Enzyme inhibitor; Infant; Topoisomerase II inhibitor; Research; Isomerases; Network; Anthracyclins; Child; Nutritional status