Causal relationship between inflammatory factors and cerebral small vessel disease: Univariate, multivariate, and summary‐data‐based mendelian randomization analysis

• Published in: Brain and behavior Vol. 14; no. 2; pp. e3399 - n/a
• Main Authors: Qiao, Tian‐Ci, Tian, Hao‐Yu, Shan, Shi‐Zhe, Shan, Li‐Li, Peng, Zheng‐Yu, Ke, Jia, Li, Meng‐Ting, Wu, Yang, Han, Yan
• Format: Journal Article
• Language: English
• Published: United States John Wiley & Sons, Inc 01.02.2024; Wiley
• Subjects: cerebral small vessel disease; Cerebral Small Vessel Diseases - diagnostic imaging; Cerebral Small Vessel Diseases - genetics; Confounding (Statistics); Datasets; Disease; DNA methylation; E-Selectin; Estimates; Gene expression; Genome-Wide Association Study; Genomes; Humans; inflammatory factors; mendelian randomization; Mendelian Randomization Analysis; Risk Factors; Software; summary‐data‐based mendelian randomization; summary-data-based mendelian randomization; cerebral small vessel disease; inflammatory factors; mendelian randomization

Objective To explore the impact of inflammatory factors on the incidence of cerebral small vessel disease (CSVD), we performed a mendelian randomization (MR) study to analyze the causal relationship between multiple inflammatory factors and CSVD imaging markers and utilized summary‐data‐based mendel...