The role of the renin‐angiotensin system in skin physiology and pathophysiology

• Published in: Experimental dermatology Vol. 29; no. 9; pp. 891 - 901
• Main Authors: Silva, Igor Maciel Souza, Assersen, Kasper Bostlund, Willadsen, Natalie Nanette, Jepsen, Julie, Artuc, Metin, Steckelings, Ulrike Muscha
• Format: Journal Article
• Language: English
• Published: Denmark Wiley Subscription Services, Inc 01.09.2020
• Subjects: ACE inhibitors; angiotensin; angiotensin AT1 receptor; Angiotensin AT1 receptors; angiotensin AT2 receptor; Angiotensin AT2 receptors; Angiotensin II; Angiotensin receptors; AT1 receptor antagonists; AT2 receptor agonists; Dystrophic epidermolysis bullosa; Epidermolysis bullosa; Fibrosis; Melanoma; Physiology; Psoriasis; Renin; Scleroderma; Skin diseases; Squamous cell carcinoma; Therapeutic targets; Wound healing; angiotensin; angiotensin AT2 receptor; angiotensin AT1 receptor; AT2 receptor agonists; AT1 receptor antagonists; ACE inhibitors

Since its first description around the year 2000, the local renin‐angiotensin system (RAS) in skin has been subject of an increasing number of studies with many additions over the last two to three years. A focus of research has been investigations on the role of cutaneous angiotensin receptors and...