Placental extracellular vesicles and pre‐eclampsia

• Published in: American journal of reproductive immunology (1989) Vol. 85; no. 2; pp. e13297 - n/a
• Main Authors: Schuster, Jessica, Cheng, Shi‐Bin, Padbury, James, Sharma, Surendra
• Format: Journal Article
• Language: English
• Published: Denmark Wiley Subscription Services, Inc 01.02.2021
• Subjects: Angiogenesis; Animals; Autophagy; Blood flow; Eclampsia; Extracellular vesicles; Extracellular Vesicles - metabolism; Female; Fetuses; Humans; Immune response; Immunity - immunology; Inflammation; Inflammation - immunology; Macromolecules; miRNA; Molecular modelling; Morbidity; Neovascularization, Pathologic; Nucleotides; Phagocytosis; Placenta; Placenta - metabolism; Pre-Eclampsia - immunology; Preeclampsia; Pregnancy; pre‐eclampsia; Proteinuria; placenta; pre-eclampsia; extracellular vesicles

Pre‐eclampsia is a hypertensive disease of pregnancy characterized by new‐onset hypertension, with either proteinuria and/or organ dysfunction. Pre‐eclampsia is a leading cause of maternal morbidity and mortality; however, the underlying cellular and molecular mechanisms are not well understood. The...