Hematopoietic stem cell transplantation therapy for refractory' Crohn disease: A systematic review and meta-analysis

• Published in: Medicine (Baltimore) Vol. 103; no. 42; p. e40144
• Main Authors: Serrano-Fernandez, Victor, Carmona-Torres, Juan Manuel, Arroyo-Rodriguez, Almudena, Lopez-Gonzalez, Angel, Rabanales-Sotos, Joseba, Laredo-Aguilera, Jose Alberto
• Format: Journal Article
• Language: English
• Published: Hagerstown, MD Lippincott Williams & Wilkins 18.10.2024
• Subjects: Crohn Disease - therapy; Hematopoietic Stem Cell Transplantation - methods; Humans; Systematic Review and Meta-Analysis; Transplantation, Autologous - methods; Treatment Outcome; hematopoietic stem cells; Crohn's disease; inflammatory bowel disease

Background: Despite the availability of numerous treatments for Crohn disease, there are patients who do not respond to any therapy, thereby diminishing their quality of life. The aim of this review is to analyze the efficacy and safety of autologous hematopoietic stem cell transplantation therapy f...