Litter Characteristics of Gilts Artificially Inseminated with Transforming Growth Factor-β

• Published in: American journal of reproductive immunology (1989) Vol. 56; no. 3; pp. 153 - 156
• Main Authors: Rhodes, Michelle, Brendemuhl, Joel H., Hansen, Peter J.
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.09.2006
• Subjects: Animals; Female; fertility; Fetal Weight - drug effects; Fetus - drug effects; Fetus - physiology; Insemination, Artificial - veterinary; litter size; Litter Size - drug effects; Male; pigs; Placenta - drug effects; Placenta - metabolism; Pregnancy; Semen - chemistry; Semen - immunology; Swine; Transforming Growth Factor beta - immunology; Transforming Growth Factor beta - pharmacology; Transforming Growth Factor beta1; Transforming growth factor-β

Problem  Semen is a rich source of transforming growth factor‐β (TGF‐β) and it has been proposed that this molecule promotes embryonic survival by modifying immune responses to promote tolerance toward paternal antigens and by inducing release of cytokines that promote embryonic development. The rol...