Depth of invasion alone as an indication for postoperative radiotherapy in small oral squamous cell carcinomas: An International Collaborative Study

• Published in: Head & neck Vol. 41; no. 6; pp. 1935 - 1942
• Main Authors: Ebrahimi, Ardalan, Gil, Ziv, Amit, Moran, Yen, Tzu‐Chen, Liao, Chun‐ta, Chaturvedi, Pankaj, Agarwal, Jai Prakash, Kowalski, Luiz P., Köhler, Hugo F., Kreppel, Matthias, Cernea, Claudio R., Brandao, Jason, Bachar, Gideon, Villaret, Andrea Bolzoni, Fliss, Dan M., Fridman, Eran, Robbins, Kevin Thomas, Shah, Jatin P., Patel, Snehal G., Clark, Jonathan R.
• Format: Journal Article
• Language: English
• Published: Hoboken, USA John Wiley & Sons, Inc 01.06.2019; Wiley Subscription Services, Inc
• Subjects: depth of invasion; Head & neck cancer; Head and neck; head and neck cancer; locoregional control; Medical prognosis; Metastases; Oral cancer; Oral carcinoma; Oral squamous cell carcinoma; Prognosis; Radiation therapy; radiotherapy; Squamous cell carcinoma; survival; tumor thickness; depth of invasion; tumor thickness; head and neck cancer; survival; locoregional control; radiotherapy; oral squamous cell carcinoma

Background We aimed to investigate whether depth of invasion (DOI) should be an independent indication for postoperative radiotherapy (PORT) in small oral squamous cell carcinomas (SCC). Methods Retrospective analysis of DOI (<5, 5 to <10, ≥10 mm) and disease‐specific survival (DSS) in a multi...