Study of Tofacitinib in Refractory Dermatomyositis: An Open‐Label Pilot Study of Ten Patients - Paik, Julie J.; Casciola‐Rosen, Livia; Shin, Joseph Yusup; Albayda, Jemima; Tiniakou, Eleni; Leung, Doris G.; Gutierrez‐Alamillo, Laura; Perin, Jamie; Florea, Liliana; Antonescu, Corina; Leung, Sherry G.; Purwin, Grazyna; et al. (Arthritis & rheumatology (Hoboken, N.J.), 2021)
Keywords: Adult; Biopsy; Chemokine CXCL10 - metabolism; Chemokine CXCL9 - metabolism; Chemokines; Clinical trials; Creatine; Creatine kinase; Criteria; CXCL10 protein; Dermatomyositis; Dermatomyositis - drug therapy; Dermatomyositis - metabolism; Dermatomyositis - physiopathology; Female; Gene expression; Gene sequencing; Health services; Humans; Immunohistochemistry; Inflammatory diseases; Interferon; Janus Kinase Inhibitors - therapeutic use; Kinases; Male; Middle Aged; Muscle, Skeletal - metabolism; Musculoskeletal diseases; Myositis; Pilot Projects; Piperidines - therapeutic use; Proof of Concept Study; Prospective Studies; Pyrimidines - therapeutic use; RNA-Seq; Safety; Sequence analysis; Skin - metabolism; Stat1 protein; STAT1 Transcription Factor - metabolism; Statistical analysis; Statistical methods; Treatment Outcome