The formation of an aberrant PAX5 transcript in a patient with mixed phenotype acute leukemia harboring der(9)t(7;9)(q11.2;p13)

• Published in: Leukemia research reports Vol. 5; no. C; pp. 14 - 17
• Main Authors: Amaki, Jun, Matsushita, Hiromichi, Kitamura, Yuka, Nagao, Ryoko, Murayama, Hiromichi, Kojima, Minoru, Ando, Kiyoshi
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ltd 2016; Elsevier
• Subjects: dert(q11.2p13); Hematology, Oncology and Palliative Medicine; MPAL; Pathology; PAX5; MPAL; dert(q11.2p13); PAX5

Abstract We experienced the case of a 56-year-old male with B-lymphoid/myeloid lineage mixed phenotype acute leukemia (MPAL). A cytogenetic analysis of the patient's bone marrow revealed a complex karyotype, including der(9)t(7;9)(q11.2;p13). We identified an aberrant PAX5 transcript, including...