Selective reactivation of human herpesvirus 6 in patients with autoimmune connective tissue diseases

• Published in: Journal of medical virology Vol. 85; no. 11; pp. 1925 - 1934
• Main Authors: Broccolo, Francesco, Drago, Francesco, Cassina, Giulia, Fava, Andrea, Fusetti, Lisa, Matteoli, Barbara, Ceccherini-Nelli, Luca, Sabbadini, Maria Grazia, Lusso, Paolo, Parodi, Aurora, Malnati, Mauro S.
• Format: Journal Article
• Language: English
• Published: Hoboken, NJ Blackwell Publishing Ltd 01.11.2013; Wiley; Wiley Subscription Services, Inc
• Subjects: Adult; Aged; Antibodies, Viral - blood; autoimmune connective tissue diseases; Autoimmune diseases; Autoimmune Diseases - complications; Biological and medical sciences; Blood - virology; Connective Tissue Diseases - complications; Cytomegalovirus; DNA, Viral - blood; Female; Fundamental and applied biological sciences. Psychology; Herpesvirus 6, Human - physiology; herpesviruses; HHV-6; Human viral diseases; Humans; Infectious diseases; Leukocytes, Mononuclear - virology; Male; Medical sciences; Microbiology; Middle Aged; Miscellaneous; plasma viremia; Roseolovirus Infections - etiology; Viral diseases; Viral Load; viral reactivation; Virology; Virus Activation; Human; Immunopathology; Connective tissue disease; Skin disease; Viremia; HHV-6; Autoimmune disease; autoimmune connective tissue diseases; viral reactivation; Infection; plasma viremia; Viral disease; herpesviruses; Human herpesvirus 6; Viral load; viral load

Viral infections have been associated with autoimmune connective tissue diseases. To evaluate whether active infection by Epstein–Barr virus (EBV), cytomegalovirus (CMV), human herpesvirus (HHV)‐6, ‐7, ‐8, as well as parvovirus B19 (B19V) occur in patients with autoimmune connective tissue diseases,...