Restricted expression of EBV latent genes and T‐lymphocyte‐detected membrane antigen in Burkitt's lymphoma cells

• Published in: The EMBO journal Vol. 5; no. 10; pp. 2599 - 2607
• Main Authors: Rowe, D.T., Rowe, M., Evan, G.I., Wallace, L.E., Farrell, P.J., Rickinson, A.B.
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group 01.10.1986
• Subjects: Antigens, Surface - genetics; Biological and medical sciences; Burkitt Lymphoma - immunology; Burkitt Lymphoma - microbiology; Cell Line; Cytotoxicity, Immunologic; Epstein-Barr virus; Fundamental and applied biological sciences. Psychology; Genes, Viral; Herpesvirus 4, Human - genetics; Humans; Microbiology; Replicative cycle, interference, host-virus relations, pathogenicity, miscellaneous strains; T-Lymphocytes - immunology; T-Lymphocytes - microbiology; Transcription, Genetic; Virology; Human; Cell culture; Herpesviridae; Burkitt lymphoma; Cytotoxicity; Cellular immunity; Epstein Barr virus; Gene expression; Infection; Virus; Viral disease; Established cell line; T»-Lymphocyte; γ-Herpesvirinae

Certain newly established Epstein‐Barr virus‐containing Burkitt's lymphoma cell lines do not express the cytotoxic T‐lymphocyte‐detected membrane antigen (LYDMA) through which EBV infection is normally controlled by the host. When the EB virus recovered from these BL lines was used to transform...