Human papillomavirus‐driven head and neck cancers in Japan during 2008–2009 and 2018–2019: The BROADEN study

• Published in: Cancer science Vol. 115; no. 8; pp. 2808 - 2818
• Main Authors: Nibu, Ken‐ichi, Oridate, Nobuhiko, Saito, Yuki, Roset, Montserrat, Forés Maresma, Marta, Cuadras, Daniel, Morais, Edith, Roberts, Craig, Chen, Ya‐Ting, Spitzer, Jacque, Sato, Kayo, Saito, Itori, Tazaki, Ichiro, Clavero, Omar, Schroeder, Lea, Alemany, Laia, Mehanna, Hisham, Mirghani, Haitham, Giuliano, Anna R., Pavón, Miquel Angel, Waterboer, Tim
• Format: Journal Article
• Language: English
• Published: England John Wiley & Sons, Inc 01.08.2024
• Subjects: Alcohol; Data collection; Deoxyribonucleic acid; DNA; Epidemiology; Genotypes; Head & neck cancer; Head and neck; HPV attributability; HPV genotype; HPV‐driven HNC; HPV‐driven vaccine; Human papillomavirus; Immunohistochemistry; INK4a protein; Laboratories; Larynx; mRNA; Oncology; Oral cavity; Oropharyngeal cancer; Oropharynx; p16 Protein; Patients; Polymerase chain reaction; Women; Japan; HPV attributability; oropharyngeal cancer; HPV‐driven HNC; HPV genotype; HPV‐driven vaccine

There is limited understanding of epidemiology and time trends of human papilloma virus (HPV)‐driven head and neck cancers (HNC) in Japan, especially outside of the oropharynx. To assess HPV‐driven HNC, a non‐interventional study (BROADEN) of HNC patients diagnosed in 2008–2009 and 2018–2019 was con...