Effects of Lowering Cerebrospinal Fluid Pressure on the Shape of the Peripapillary Retina in Intracranial Hypertension

• Published in: Investigative ophthalmology & visual science Vol. 55; no. 12; pp. 8223 - 8231
• Main Authors: Sibony, P., Kupersmith, M. J., Honkanen, R., Rohlf, F. J., Torab-Parhiz, A.
• Format: Journal Article
• Language: English
• Published: United States The Association for Research in Vision and Ophthalmology 18.11.2014
• Subjects: Adolescent; Adult; Analysis of Variance; Basement Membrane - pathology; Case-Control Studies; Cerebrospinal Fluid Pressure - physiology; Cerebrospinal Fluid Shunts; Female; Humans; Intracranial Hypertension - complications; Intracranial Hypertension - physiopathology; Intracranial Hypertension - surgery; Male; Middle Aged; Papilledema - etiology; Papilledema - physiopathology; Retinal Ganglion Cells - pathology; Retinal Neurons - pathology; Retinal Pigment Epithelium - pathology; Spinal Puncture; Tomography, Optical Coherence; Young Adult; papilledema; optical coherence tomography; idiopathic intracranial hypertension; optic nerve; cerebrospinal fluid shunts; geometric morphometrics

To analyze the deformations of the peripapillary retinal pigment epithelium-basement membrane (ppRPE/BM) layer in response to procedures that lower intracranial pressure (ICP). Second, to demonstrate how shape changes may complement the mean retinal nerve fiber layer (RNFL) thickness as a measure of...