Low serum free IL-18 is a novel potential marker for predicting infectious events in patients at dialysis initiation

• Published in: Clinical kidney journal Vol. 18; no. 5; p. sfaf094
• Main Authors: Tawara-Iida, Takashi, Usui, Joichi, Ebihara, Itaru, Ishizu, Takashi, Kobayashi, Masaki, Maeda, Yoshitaka, Kobayashi, Hiroaki, Yamagata, Kunihiro, Nakamura, Hideko, Takada, Kenji, Kozaki, Koichi, Iwabuchi, Satoshi, Iitsuka, Tadashi, Nishiki, Kenta, Takasaki, Hideaki, Takita, Takashi, Nakajima, Masami, Honma, Sumiko, Akai, Youichi, Ishizuka, Genzou, Issiki, Koichi, Saito, Takako, Iwamoto, Hitoshi, Ohishi, Akira, Ohtsuka, Masakazu, Ono, Atsushi, Kashiwabara, Hidehiko, Kanekawa, Takuro, Kanamori, Naoaki, Kaneda, Fumika, Kikuchi, Hiroshi, Kubo, Masashi, Kurosawa, Hiromi, Shiraishi, Takeshi, Shiigai, Tatsuo, Shima, Masayoshi, Takahashi, Tokuo, Matsukawa, Hideki, Tokoi, Minoru, Tsunematsu, Sadao, Tsuruta, Atsushi, Deguchi, Masao, Hayakawa, Masahiro, Hiroi, Makoto, Maeda, Nobuki, Hoshino, Takanobu, Yamaguchi, Tetsu, Yamada, Kota, Takeda, Atsushi, Takahashi, Ikuo, Yuhara, Takamichi, Kondo, Tadashi, Ooba, Syoji, Ogura, Yasunobu, Tachibana, Hisaya, Ookawa, Hiroshi, Fujii, Toshihiro
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 01.05.2025
• Subjects: Analysis; Communicable diseases; Development and progression; Health aspects; Infection; Interleukins; Japan; Medical research; Medicine, Experimental; Mortality; Original; Prognosis; Protein binding; Rankings; Japan; infection; dialysis initiation; multicenter prospective cohort study; free IL-18

Compared to the general population, individuals who are undergoing hemodialysis are at a higher risk of contracting severe infectious diseases, and their mortality rate from infectious diseases is also higher. We investigated the serum free interleukin-18 [free state of interleukin-18 (IL-18)] conce...