Ionic mechanism of forskolin-induced liquid secretion by porcine bronchi

• Published in: American journal of physiology. Lung cellular and molecular physiology Vol. 290; no. 1; pp. L97 - L104
• Main Authors: Ballard, Stephen T, Trout, Laura, Garrison, Jennifer, Inglis, Sarah K
• Format: Journal Article
• Language: English
• Published: United States 01.01.2006
• Subjects: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid - pharmacology; Animals; Anions - metabolism; Bicarbonates - antagonists & inhibitors; Bicarbonates - metabolism; Bronchi - drug effects; Bronchi - secretion; Bumetanide - administration & dosage; Bumetanide - pharmacology; Chlorides - metabolism; Colforsin - pharmacology; Drug Synergism; Instillation, Drug; Ion Channels - antagonists & inhibitors; Sodium Potassium Chloride Symporter Inhibitors - administration & dosage; Sodium Potassium Chloride Symporter Inhibitors - pharmacology; Swine

1 Department of Physiology, College of Medicine, University of South Alabama, Mobile, Alabama; and 2 Maternal and Child Health Sciences, Ninewells Hospital, Dundee University, Dundee, United Kingdom Submitted 11 April 2005 ; accepted in final form 4 August 2005 cAMP-elevating agents such as forskoli...