Abnormal gut microbiota composition contributes to cognitive dysfunction in SAMP8 mice

• Published in: Aging (Albany, NY.) Vol. 10; no. 6; pp. 1257 - 1267
• Main Authors: Zhan, Gaofeng, Yang, Ning, Li, Shan, Huang, Niannian, Fang, Xi, Zhang, Jie, Zhu, Bin, Yang, Ling, Yang, Chun, Luo, Ailin
• Format: Journal Article
• Language: English
• Published: United States Impact Journals 10.06.2018
• Subjects: Research Paper; Alzheimer’s disease; pseudo germ-free mice; cognitive dysfunction; gut microbiota; SAMP8

Alzheimer's disease is characterized by cognitive dysfunction and aging is an important predisposing factor; however, the pathological and therapeutic mechanisms are not fully understood. Recently, the role of gut microbiota in Alzheimer's disease has received increasing attention. The cog...