The Contributions of Near Work and Outdoor Activity to the Correlation Between Siblings in the Collaborative Longitudinal Evaluation of Ethnicity and Refractive Error (CLEERE) Study

We determined the correlation between sibling refractive errors adjusted for shared and unique environmental factors using data from the Collaborative Longitudinal Evaluation of Ethnicity and Refractive Error (CLEERE) Study. Refractive error from subjects' last study visits was used to estimate...

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Published inInvestigative ophthalmology & visual science Vol. 55; no. 10; pp. 6333 - 6339
Main Authors Jones-Jordan, Lisa A., Sinnott, Loraine T., Graham, Nicholas D., Cotter, Susan A., Kleinstein, Robert N., Manny, Ruth E., Mutti, Donald O., Twelker, J. Daniel, Zadnik, Karla
Format Journal Article
LanguageEnglish
Published United States The Association for Research in Vision and Ophthalmology 10.10.2014
Subjects
Activities of Daily Living
Adolescent
Child
Disease Progression
Environmental Exposure
Ethnic Groups
Female
Follow-Up Studies
Humans
Male
Motor Activity
Prevalence
Refraction, Ocular - physiology
Refractive Errors - ethnology
Refractive Errors - etiology
Refractive Errors - genetics
Retrospective Studies
Risk Factors
Siblings
United States - epidemiology
United States
myopia
heritability
pediatric
Online AccessGet full text
ISSN1552-5783
0146-0404
1552-5783
DOI10.1167/iovs.14-14640

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Abstract We determined the correlation between sibling refractive errors adjusted for shared and unique environmental factors using data from the Collaborative Longitudinal Evaluation of Ethnicity and Refractive Error (CLEERE) Study. Refractive error from subjects' last study visits was used to estimate the intraclass correlation coefficient (ICC) between siblings. The correlation models used environmental factors (diopter-hours and outdoor/sports activity) assessed annually from parents by survey to adjust for shared and unique environmental exposures when estimating the heritability of refractive error (2*ICC). Data from 700 families contributed to the between-sibling correlation for spherical equivalent refractive error. The mean age of the children at the last visit was 13.3 ± 0.90 years. Siblings engaged in similar amounts of near and outdoor activities (correlations ranged from 0.40-0.76). The ICC for spherical equivalent, controlling for age, sex, ethnicity, and site was 0.367 (95% confidence interval [CI] = 0.304, 0.420), with an estimated heritability of no more than 0.733. After controlling for these variables, and near and outdoor/sports activities, the resulting ICC was 0.364 (95% CI = 0.304, 0.420; estimated heritability no more than 0.728, 95% CI = 0.608, 0.850). The ICCs did not differ significantly between male-female and single sex pairs. Adjusting for shared family and unique, child-specific environmental factors only reduced the estimate of refractive error correlation between siblings by 0.5%. Consistent with a lack of association between myopia progression and either near work or outdoor/sports activity, substantial common environmental exposures had little effect on this correlation. Genetic effects appear to have the major role in determining the similarity of refractive error between siblings.
AbstractList Using sibling refractive error and visual activity data, the effects of environmental data on heritability are assessed in the Collaborative Longitudinal Evaluation of Ethnicity and Refractive Error Study.
We determined the correlation between sibling refractive errors adjusted for shared and unique environmental factors using data from the Collaborative Longitudinal Evaluation of Ethnicity and Refractive Error (CLEERE) Study.PURPOSEWe determined the correlation between sibling refractive errors adjusted for shared and unique environmental factors using data from the Collaborative Longitudinal Evaluation of Ethnicity and Refractive Error (CLEERE) Study.Refractive error from subjects' last study visits was used to estimate the intraclass correlation coefficient (ICC) between siblings. The correlation models used environmental factors (diopter-hours and outdoor/sports activity) assessed annually from parents by survey to adjust for shared and unique environmental exposures when estimating the heritability of refractive error (2*ICC).METHODSRefractive error from subjects' last study visits was used to estimate the intraclass correlation coefficient (ICC) between siblings. The correlation models used environmental factors (diopter-hours and outdoor/sports activity) assessed annually from parents by survey to adjust for shared and unique environmental exposures when estimating the heritability of refractive error (2*ICC).Data from 700 families contributed to the between-sibling correlation for spherical equivalent refractive error. The mean age of the children at the last visit was 13.3 ± 0.90 years. Siblings engaged in similar amounts of near and outdoor activities (correlations ranged from 0.40-0.76). The ICC for spherical equivalent, controlling for age, sex, ethnicity, and site was 0.367 (95% confidence interval [CI] = 0.304, 0.420), with an estimated heritability of no more than 0.733. After controlling for these variables, and near and outdoor/sports activities, the resulting ICC was 0.364 (95% CI = 0.304, 0.420; estimated heritability no more than 0.728, 95% CI = 0.608, 0.850). The ICCs did not differ significantly between male-female and single sex pairs.RESULTSData from 700 families contributed to the between-sibling correlation for spherical equivalent refractive error. The mean age of the children at the last visit was 13.3 ± 0.90 years. Siblings engaged in similar amounts of near and outdoor activities (correlations ranged from 0.40-0.76). The ICC for spherical equivalent, controlling for age, sex, ethnicity, and site was 0.367 (95% confidence interval [CI] = 0.304, 0.420), with an estimated heritability of no more than 0.733. After controlling for these variables, and near and outdoor/sports activities, the resulting ICC was 0.364 (95% CI = 0.304, 0.420; estimated heritability no more than 0.728, 95% CI = 0.608, 0.850). The ICCs did not differ significantly between male-female and single sex pairs.Adjusting for shared family and unique, child-specific environmental factors only reduced the estimate of refractive error correlation between siblings by 0.5%. Consistent with a lack of association between myopia progression and either near work or outdoor/sports activity, substantial common environmental exposures had little effect on this correlation. Genetic effects appear to have the major role in determining the similarity of refractive error between siblings.CONCLUSIONSAdjusting for shared family and unique, child-specific environmental factors only reduced the estimate of refractive error correlation between siblings by 0.5%. Consistent with a lack of association between myopia progression and either near work or outdoor/sports activity, substantial common environmental exposures had little effect on this correlation. Genetic effects appear to have the major role in determining the similarity of refractive error between siblings.
We determined the correlation between sibling refractive errors adjusted for shared and unique environmental factors using data from the Collaborative Longitudinal Evaluation of Ethnicity and Refractive Error (CLEERE) Study. Refractive error from subjects' last study visits was used to estimate the intraclass correlation coefficient (ICC) between siblings. The correlation models used environmental factors (diopter-hours and outdoor/sports activity) assessed annually from parents by survey to adjust for shared and unique environmental exposures when estimating the heritability of refractive error (2*ICC). Data from 700 families contributed to the between-sibling correlation for spherical equivalent refractive error. The mean age of the children at the last visit was 13.3 ± 0.90 years. Siblings engaged in similar amounts of near and outdoor activities (correlations ranged from 0.40-0.76). The ICC for spherical equivalent, controlling for age, sex, ethnicity, and site was 0.367 (95% confidence interval [CI] = 0.304, 0.420), with an estimated heritability of no more than 0.733. After controlling for these variables, and near and outdoor/sports activities, the resulting ICC was 0.364 (95% CI = 0.304, 0.420; estimated heritability no more than 0.728, 95% CI = 0.608, 0.850). The ICCs did not differ significantly between male-female and single sex pairs. Adjusting for shared family and unique, child-specific environmental factors only reduced the estimate of refractive error correlation between siblings by 0.5%. Consistent with a lack of association between myopia progression and either near work or outdoor/sports activity, substantial common environmental exposures had little effect on this correlation. Genetic effects appear to have the major role in determining the similarity of refractive error between siblings.
Author Kleinstein, Robert N.
Jones-Jordan, Lisa A.
Twelker, J. Daniel
Graham, Nicholas D.
Manny, Ruth E.
Zadnik, Karla
Cotter, Susan A.
Mutti, Donald O.
Sinnott, Loraine T.
AuthorAffiliation 6 University of Arizona Department of Ophthalmology and Vision Science, Tucson, Arizona, United States
4 University of Alabama at Birmingham School of Optometry, Birmingham, Alabama, United States
5 University of Houston College of Optometry, Houston, Texas, United States
3 Marshall B. Ketchum University, Fullerton, California, United States
1 The Ohio State University College of Optometry, Columbus, Ohio, United States
2 Private Practice, Matthews, North Carolina, United States
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Mutti, Donald O
Jones-Jordan, Lisa A
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Messer, Dawn
Hullett, Sandral
Crossnoe, Connie J
Batres, Mamie
Sims, Janene
Taylor, Samuel
Moeschberger, Melvin L
Thatcher, Jodi M Malone
Shipp, Melvin D
Cotter, Susan A
Twelker, J Daniel
Weeks, Raphael
Wensveen, Janice M
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Kleinstein, Robert N
Rahmani, Meliha
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Lee, Gen
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Kwon, Soonsi
Leonhardt, Tracy
Chu, Raymond J
Chang, Jessica
Maeda, Raymond
Crescioni, Mabel
Huang, Kristine
Walker, Terry W
Tom, Stephanie L
Emerson, Rachael
Williams, Sandra
Hayes, John
Lee, John
Sinnott, Loraine
Garvey, Katie
Swartzendruber, Julie N
Kim, Ailene
Chu, Connie
Lee, Robert J
Wessel, Pamela
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Keywords myopia
heritability
pediatric
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  text: 2014-10-10
  day: 10
PublicationDecade 2010
PublicationPlace United States
PublicationPlace_xml – name: United States
PublicationTitle Investigative ophthalmology & visual science
PublicationTitleAlternate Invest Ophthalmol Vis Sci
PublicationYear 2014
Publisher The Association for Research in Vision and Ophthalmology
Publisher_xml – name: The Association for Research in Vision and Ophthalmology
References 17652719 - Invest Ophthalmol Vis Sci. 2007 Aug;48(8):3524-32
17205325 - Hum Genet. 2007 May;121(3-4):511-20
23396134 - Nat Genet. 2013 Mar;45(3):314-8
8600894 - Arch Ophthalmol. 1996 Mar;114(3):326-32
8265177 - Ophthalmic Physiol Opt. 1993 Jul;13(3):316-9
17135339 - Br J Ophthalmol. 2007 Jun;91(6):781-4
11734523 - Br J Ophthalmol. 2001 Dec;85(12):1470-6
23314127 - Optom Vis Sci. 2013 Feb;90(2):148-55
11328732 - Invest Ophthalmol Vis Sci. 2001 May;42(6):1232-6
23468642 - PLoS Genet. 2013;9(2):e1003299
12147586 - Invest Ophthalmol Vis Sci. 2002 Aug;43(8):2566-71
15851555 - Invest Ophthalmol Vis Sci. 2005 May;46(5):1588-92
20020241 - Jpn J Ophthalmol. 2009 Nov;53(6):615-22
3049225 - Genet Epidemiol. 1988;5(3):171-81
22491403 - Invest Ophthalmol Vis Sci. 2012 May;53(6):2856-65
12454029 - Invest Ophthalmol Vis Sci. 2002 Dec;43(12):3633-40
17724179 - Invest Ophthalmol Vis Sci. 2007 Sep;48(9):4002-6
10082056 - Optom Vis Sci. 1999 Feb;76(2):102-7
18757506 - Invest Ophthalmol Vis Sci. 2009 Jan;50(1):126-31
17525178 - Invest Ophthalmol Vis Sci. 2007 Jun;48(6):2510-9
10892850 - Invest Ophthalmol Vis Sci. 2000 Jul;41(8):2103-7
11709020 - Arch Ophthalmol. 2001 Nov;119(11):1679-85
15555525 - Prog Retin Eye Res. 2005 Jan;24(1):1-38
8233371 - Optom Vis Sci. 1993 Sep;70(9):750-8
23620424 - Invest Ophthalmol Vis Sci. 2013 May;54(5):3644-9
19433716 - Arch Ophthalmol. 2009 May;127(5):649-55
10416932 - Optom Vis Sci. 1999 Jun;76(6):381-6
22562184 - Eye (Lond). 2012 Jul;26(7):911-8
References_xml – reference: 22491403 - Invest Ophthalmol Vis Sci. 2012 May;53(6):2856-65
– reference: 23396134 - Nat Genet. 2013 Mar;45(3):314-8
– reference: 11709020 - Arch Ophthalmol. 2001 Nov;119(11):1679-85
– reference: 19433716 - Arch Ophthalmol. 2009 May;127(5):649-55
– reference: 17205325 - Hum Genet. 2007 May;121(3-4):511-20
– reference: 17652719 - Invest Ophthalmol Vis Sci. 2007 Aug;48(8):3524-32
– reference: 10082056 - Optom Vis Sci. 1999 Feb;76(2):102-7
– reference: 15851555 - Invest Ophthalmol Vis Sci. 2005 May;46(5):1588-92
– reference: 23314127 - Optom Vis Sci. 2013 Feb;90(2):148-55
– reference: 12147586 - Invest Ophthalmol Vis Sci. 2002 Aug;43(8):2566-71
– reference: 17724179 - Invest Ophthalmol Vis Sci. 2007 Sep;48(9):4002-6
– reference: 11328732 - Invest Ophthalmol Vis Sci. 2001 May;42(6):1232-6
– reference: 8233371 - Optom Vis Sci. 1993 Sep;70(9):750-8
– reference: 8265177 - Ophthalmic Physiol Opt. 1993 Jul;13(3):316-9
– reference: 17135339 - Br J Ophthalmol. 2007 Jun;91(6):781-4
– reference: 17525178 - Invest Ophthalmol Vis Sci. 2007 Jun;48(6):2510-9
– reference: 10416932 - Optom Vis Sci. 1999 Jun;76(6):381-6
– reference: 10892850 - Invest Ophthalmol Vis Sci. 2000 Jul;41(8):2103-7
– reference: 3049225 - Genet Epidemiol. 1988;5(3):171-81
– reference: 20020241 - Jpn J Ophthalmol. 2009 Nov;53(6):615-22
– reference: 18757506 - Invest Ophthalmol Vis Sci. 2009 Jan;50(1):126-31
– reference: 22562184 - Eye (Lond). 2012 Jul;26(7):911-8
– reference: 15555525 - Prog Retin Eye Res. 2005 Jan;24(1):1-38
– reference: 11734523 - Br J Ophthalmol. 2001 Dec;85(12):1470-6
– reference: 8600894 - Arch Ophthalmol. 1996 Mar;114(3):326-32
– reference: 23468642 - PLoS Genet. 2013;9(2):e1003299
– reference: 12454029 - Invest Ophthalmol Vis Sci. 2002 Dec;43(12):3633-40
– reference: 23620424 - Invest Ophthalmol Vis Sci. 2013 May;54(5):3644-9
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Snippet We determined the correlation between sibling refractive errors adjusted for shared and unique environmental factors using data from the Collaborative...
Using sibling refractive error and visual activity data, the effects of environmental data on heritability are assessed in the Collaborative Longitudinal...
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StartPage 6333
SubjectTerms Activities of Daily Living
Adolescent
Child
Disease Progression
Environmental Exposure
Ethnic Groups
Female
Follow-Up Studies
Humans
Male
Motor Activity
Prevalence
Refraction, Ocular - physiology
Refractive Errors - ethnology
Refractive Errors - etiology
Refractive Errors - genetics
Retrospective Studies
Risk Factors
Siblings
United States - epidemiology
Title The Contributions of Near Work and Outdoor Activity to the Correlation Between Siblings in the Collaborative Longitudinal Evaluation of Ethnicity and Refractive Error (CLEERE) Study
URI https://www.ncbi.nlm.nih.gov/pubmed/25205866
https://www.proquest.com/docview/1612289571
https://pubmed.ncbi.nlm.nih.gov/PMC4193758
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