Dopaminergic genotype influences spatial bias in healthy adults

• Published in: Neuropsychologia Vol. 48; no. 9; pp. 2458 - 2464
• Main Authors: Greene, Ciara M., Robertson, Ian H., Gill, Michael, Bellgrove, Mark A.
• Format: Journal Article
• Language: English
• Published: Kidlington Elsevier Ltd 01.07.2010; Elsevier
• Subjects: 3' Untranslated Regions - genetics; Adolescent; Analysis of Variance; Attention - physiology; Behavioral psychophysiology; Biological and medical sciences; DAT1; DBH; Dopamine; Dopamine - metabolism; Dopamine beta-Hydroxylase - genetics; Dopamine Plasma Membrane Transport Proteins - genetics; Female; Fundamental and applied biological sciences. Psychology; Genotype; Humans; Landmark; Male; Neurotransmission and behavior; Noradrenaline; Perceptual Disorders - genetics; Perceptual Disorders - physiopathology; Psychology. Psychoanalysis. Psychiatry; Psychology. Psychophysiology; Saliva - metabolism; Space Perception; Spatial attention; Terminal Repeat Sequences - genetics; Trinucleotide Repeat Expansion - genetics; Young Adult; Dopamine; DBH; DAT1; Noradrenaline; Spatial attention; Landmark; Human; Healthy subject; Spatial ability; Genotype; Cognition; Space perception; Catecholamine; Genetic determinism; Neurotransmitter; Genetics; Adult; Norepinephrine

Asymmetries of spatial attention are observed in both clinical and non-clinical populations. While lesions of the right hemisphere frequently result in symptoms of left neglect (right bias), the opposite pattern is often observed in healthy subjects, a phenomenon known as pseudoneglect. Pharmacologi...